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Articles Published Processes
6/30/2015 8:56:00 AM | Browse: 995 | Download: 1520
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Received |
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2014-10-18 13:14 |
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Peer-Review Started |
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2014-10-20 08:08 |
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To Make the First Decision |
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2014-12-17 11:23 |
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Return for Revision |
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2014-12-19 14:36 |
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Revised |
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2015-01-09 17:25 |
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Second Decision |
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2015-03-16 17:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-04-07 15:51 |
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Articles in Press |
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2015-04-07 15:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-04-27 08:27 |
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Typeset the Manuscript |
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2015-06-12 14:29 |
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Publish the Manuscript Online |
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2015-06-30 08:56 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Basic Study |
| Article Title |
New model for cardiomyocyte sheet transplantation using a virus-cell fusion technique
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yuto Takahashi, Daihachiro Tomotsune, Sakiko Takizawa, Fengming Yue, Mika Nagai, Tadayuki Yokoyama, Kanji Hirashima and Katsunori Sasaki |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Scientific Research from the Japanese Ministry of Education, Science and Sports |
24240076 |
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| Corresponding Author |
Katsunori Sasaki, MD, Department of Histology and Embryology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan. katsmd@shinshu-u.ac.jp |
| Key Words |
Cardiomyocyte sheet; Latissimus dorsi; Hemagglutinating virus of Japan envelope; Cell fusion; NaOH; Maceration; Cellular transplantation method |
| Core Tip |
It is very important to produce close contacts between transplanted cell sheets and host cells without fibrous invasion for tissue reconstruction and function. Unfortunately, cellular transplantation research has not focused on this problem and convenient methods have not yet been developed. In this study using hemagglutinating virus of Japan envelope, transplanted cardiomyocyte sheets were placed in direct contact with host skeletal muscles. By adding NaOH maceration of connective tissues, rich, largely-movable, beating domains were observed. Histological observations revealed successful formation of close contacts bet?ween the two cell types. This paper proposes a new idea of introducing artificial cell fusion into cellular transplantation methods. |
| Publish Date |
2015-06-30 08:56 |
| Citation |
Takahashi Y, Tomotsune D, Takizawa S, Yue F, Nagai M, Yokoyama T, Hirashima K, Sasaki K. New model for cardiomyocyte sheet transplantation using a virus-cell fusion technique. World J Stem Cells 2015; 7(5): 883-893 |
| URL |
http://www.wjgnet.com/1948-0210/full/v7/i5/883.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v7.i5.883 |
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