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6/30/2015 8:56:00 AM | Browse: 433 | Download: 632
Publication Name World Journal of Stem Cells
Manuscript ID 14651
Country/Territory Japan
Received
2014-10-18 13:14
Peer-Review Started
2014-10-20 08:08
To Make the First Decision
2014-12-17 11:23
Return for Revision
2014-12-19 14:36
Revised
2015-01-09 17:25
Second Decision
2015-03-16 17:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-04-07 15:51
Articles in Press
2015-04-07 15:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-04-27 08:27
Typeset the Manuscript
2015-06-12 14:29
Publish the Manuscript Online
2015-06-30 08:56
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Basic Study
Article Title New model for cardiomyocyte sheet transplantation using a virus-cell fusion technique
Manuscript Source Invited Manuscript
All Author List Yuto Takahashi, Daihachiro Tomotsune, Sakiko Takizawa, Fengming Yue, Mika Nagai, Tadayuki Yokoyama, Kanji Hirashima and Katsunori Sasaki
Funding Agency and Grant Number
Funding Agency Grant Number
Scientific Research from the Japanese Ministry of Education, Science and Sports 24240076
Corresponding author Katsunori Sasaki, MD, Department of Histology and Embryology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan. katsmd@shinshu-u.ac.jp
Key Words Cardiomyocyte sheet; Latissimus dorsi; Hemagglutinating virus of Japan envelope; Cell fusion; NaOH; Maceration; Cellular transplantation method
Core Tip It is very important to produce close contacts between transplanted cell sheets and host cells without fibrous invasion for tissue reconstruction and function. Unfortunately, cellular transplantation research has not focused on this problem and convenient methods have not yet been developed. In this study using hemagglutinating virus of Japan envelope, transplanted cardiomyocyte sheets were placed in direct contact with host skeletal muscles. By adding NaOH maceration of connective tissues, rich, largely-movable, beating domains were observed. Histological observations revealed successful formation of close contacts bet?ween the two cell types. This paper proposes a new idea of introducing artificial cell fusion into cellular transplantation methods.
Publish Date 2015-06-30 08:56
Citation Takahashi Y, Tomotsune D, Takizawa S, Yue F, Nagai M, Yokoyama T, Hirashima K, Sasaki K. New model for cardiomyocyte sheet transplantation using a virus-cell fusion technique. World J Stem Cells 2015; 7(5): 883-893
Url http://www.wjgnet.com/1948-0210/full/v7/i5/883.htm
DOI http://dx.doi.org/10.4252/wjsc.v7.i5.883
Full Article (PDF) WJSC-7-883.pdf
Full Article (Word) WJSC-7-883.doc
Manuscript File 14651-Review .doc
Answering Reviewers 14651-Answering reviewers.pdf
Biostatistics Review Certificate 14651-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 14651-Conflict-of-interest statement.pdf
Copyright License Agreement 14651-Copyright assignment.pdf
Data Sharing Statement 14651-Data sharing statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 14651-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 14651-Institutional review board statement.pdf
Peer-review Report 14651-Peer-review(s).pdf
Scientific Misconduct Check 14651-Scientific misconduct check.pdf
Scientific Editor Work List 14651-Scientific editor work list.pdf