Publication Name	World Journal of Gastroenterology
Manuscript ID	14675
Country	China

Received	2014-10-20 09:36
Peer-Review Started	2014-10-20 17:16
First Decision by Editorial Office Director
Return for Revision	2014-12-16 16:19
Revised	2014-12-29 20:01
Publication Fee Transferred
Second Decision by Editor	2015-01-06 14:04
Second Decision by Editor-in-Chief	2015-01-07 09:44
Final Decision by Editorial Office Director	2015-01-30 18:23
Articles in Press	2015-01-30 18:34
Edit the Manuscript by Language Editor	2015-02-08 22:49
Typeset the Manuscript	2015-03-09 09:34
Publish the Manuscript Online	2015-03-19 16:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of non-alcoholic fatty liver disease
Manuscript Source	Unsolicited Manuscript
All Author List	Shao-Ren Zhang and Xiao-Ming Fan
Funding Agency and Grant Number	Funding Agency Grant Number Key Clinical Discipline Construction of Shanghai Municipality of China ZK2012B20
Corresponding Author	Xiao-Ming Fan, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Jinshan Hospital of Fudan University, No. 1508 Longhang Road, Shanghai 201508, China. xiaomingfan57@sina.com
Key Words	Non-alcoholic fatty liver disease; Ghrelin-ghrelin O-acyltransferase system; Lipid metabolism; Insulin resistance; Energy homeostasis
Core Tip	Nonalcoholic fatty liver disease (NAFLD) is a progressive disorder that can lead to impaired liver function and, ultimately, liver failure. The ghrelin-ghrelin O-acyltransferase (GOAT) system has recently been found to play a crucial role in both the development of steatosis and progression to nonalcoholic steatohepatitis. This review probes into the possible relationship between ghrelin-GOAT system and NAFLD, from the perspective of the potential mechanism of how ghrelin-GOAT system brings about insulin resistance and other aspects concerning NAFLD.
Publish Date	2015-03-19 16:57
Citation	Zhang SR, Fan XM. Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of nonalcoholic fatty liver disease. World J Gastroenterol 2015; 21(11): 3214-3222
URL	http://www.wjgnet.com/1007-9327/full/v21/i11/3214.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i11.3214

Full Article (PDF)	WJG-21-3214.pdf
Full Article (Word)	WJG-21-3214.doc
Manuscript File	14675-Review.doc
Answering Reviewers	14675-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14675-Conflict-of-interest statement.pdf
Copyright License Agreement	14675-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	14675-Language certificate.PDF
Peer-review Report	14675-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	14675-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check	14675-CrossCheck.jpg
Scientific Editor Work List	14675-Scientific editor work list.pdf