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Publication Name World Journal of Obstetrics and Gynecology
Manuscript ID 1472
Country Belgium
Received
2012-12-13 14:47
Peer-Review Started
2012-12-13 15:59
To Make the First Decision
2013-03-11 15:15
Return for Revision
2013-03-19 17:18
Revised
Second Decision
2013-07-05 10:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-07-05 12:11
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-08-09 19:00
Publish the Manuscript Online
2013-11-17 20:09
ISSN 2218-6220 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Obstetrics & Gynecology
Manuscript Type Topic Highlights
Article Title Pharmacology of cancer chemotherapy drugs for hyperthermic intraperitoneal peroperative chemotherapy in epithelial ovarian cancer
Manuscript Source Invited Manuscript
All Author List Kurt Van der Speeten, Anthony O Stuart and Paul H Sugarbaker
Funding Agency and Grant Number
Corresponding Author Kurt Van der Speeten, MD, PhD, Department of Surgical Oncology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, 3600 Genk, Belgium. kurt.vanderspeeten@zol.be
Key Words Intraperitoneal chemotherapy; Epithelial ovarian cancer; Ifosfamide; Cisplatin; Carboplatin; Taxanes; Pharmacokinetics; Pharmacodynamics
Core Tip Intraperitoneal (IP) chemotherapy is an important adjuvant treatment strategy in patients with advanced epithelial ovarian cancer. Although the clinical benefits have been demonstrated both in phase Ⅱ and Ⅲ trials, the pharmacologic rationale for this treatment strategy needs to be clarified. This manuscript reviews the pharmacokinetic and pharmacodynamic rationale of IP chemotherapy and analyzes the available data.
Publish Date 2013-11-17 20:09
Citation Van der Speeten K, Stuart AO, Sugarbaker PH. Pharmacology of cancer chemotherapy drugs for hyperthermic intraperitoneal peroperative chemotherapy in epithelial ovarian cancer. World J Obstet Gynecol 2013; 2(4): 143-152
URL http://www.wjgnet.com/2218-6220/full/v2/i4/143.htm
DOI http://dx.doi.org/10.5317/wjog.v2.i4.143
Full Article (PDF) WJOG-2-143.pdf
Manuscript File 1472-Review.doc
Answering Reviewers 1472-Answering reviewers.pdf
Copyright License Agreement 1472-Copyright assignment.pdf
Peer-review Report 1472-Peer review(s).pdf
Scientific Editor Work List 1472-Scientific editor work list.doc