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Articles Published Processes
4/27/2015 4:29:00 PM | Browse: 1144 | Download: 2016
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Received |
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2014-10-22 21:45 |
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Peer-Review Started |
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2014-10-28 08:49 |
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To Make the First Decision |
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2014-12-11 20:20 |
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Return for Revision |
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2014-12-24 08:57 |
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Revised |
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2015-01-04 16:06 |
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Second Decision |
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2015-02-10 21:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-02-11 15:01 |
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Articles in Press |
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2015-02-11 16:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-03-10 17:46 |
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Typeset the Manuscript |
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2015-04-14 15:50 |
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Publish the Manuscript Online |
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2015-04-27 16:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Laboratory Technology |
| Manuscript Type |
Basic Study |
| Article Title |
Comparison of two different laparotomy methods for modeling rabbit VX2 hepatocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhu Chen, Zhen Kang, En-Hua Xiao, Min Tong, Yu-Dong Xiao and Hua-Bing Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Hunan Province, China |
14JJ2034 |
| Development and Reform Commission of Hunan Province, China |
2013-1199 |
| Science and Technology Department of Hunan Province, China |
2014TT2017 |
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| Corresponding Author |
En-Hua Xiao, MD, Professor, Department of Radiology, the Second Xiangya Hospital, Central South University, No. 139 Renmin Zhong Lu, Fu Rong District, Changsha 410011, Hunan Province, China. cjr.xiaoenhua@vip.163.com |
| Key Words |
Rabbit VX2 hepatocarcinoma; Laparotomy; Modeling; Magnetic resonance imaging |
| Core Tip |
A crucial issue in studying liver cancer is the establishment of an animal model to simulate human liver cancer. There are various ways to establish rabbit VX2 hepatocarcinoma, and using an open laparotomy implant is a widely adopted classical method. We injected tumor fragments into the left lobe of the rabbit liver, deviating from the abdominal wall using a 15 G syringe needle instead of building a sinus using tweezers. This improved method is recommended because of advantages such as decreased injury to the liver, shorter operation time, lower death rates, reduced abdominal cavity implantation and fewer abdominal wall invasions. |
| Publish Date |
2015-04-27 16:22 |
| Citation |
Chen Z, Kang Z, Xiao EH, Tong M, Xiao YD, Li HB. Comparison of two different laparotomy methods for modeling rabbit VX2 hepatocarcinoma. World J Gastroenterol 2015; 21(16): 4875-4882 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i16/4875.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i16.4875 |
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