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4/28/2015 10:11:00 AM | Browse: 497 | Download: 930
Publication Name World Journal of Meta-Analysis
Manuscript ID 14764
Country of Manuscript Source United States
Received
2014-10-23 08:53
Peer-Review Started
2014-10-24 17:36
To Make the First Decision
2014-12-26 13:14
Return for Revision
2014-12-30 16:12
Revised
2015-01-03 01:49
Second Decision
2015-01-08 17:01
Accepted by Journal Editor-in-Chief
2015-01-10 07:41
Accepted by Company Editor-in-Chief
2015-01-19 13:41
Articles in Press
2015-01-19 13:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-02-06 14:05
Publish the Manuscript Online
2015-04-28 10:11
ISSN 2308-3840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Systematic Review
Article Title Meta-analysis of single strain probiotics for the eradication of Helicobacter pylori and prevention of adverse events
Manuscript Source Invited Manuscript
All Author List Lynne V McFarland, Peter Malfertheiner, Ying Huang and Lin Wang
Funding Agency and Grant Number
Correspondence To Lynne V McFarland, PhD, Health Services Research and Development, VA Puget Sound Health Care System, Department of Veterans Affairs, Metropolitan Park West, 1100 Olive Way #1400, Seattle, WA 98101, United States. lvmcfarl@u.washington.edu
Keywords Probiotics; Safety; Saccharomyces boulardii; Helicobacter pylori; Meta-analysis; Adverse reactions; Diarrhea; Lactobacillus rhamnosus; Randomized clinical trials
Core Tip A meta-analysis was conducted (1960-2014) for randomized clinical trials testing single strained probiotics as an adjunct to standard Helicobacter pylori (H. pylori) eradication therapy. Of the single strains with multiple trials, only one significantly improved H. pylori eradication rates {Saccharomyces boulardii (S. boulardii) I-745 [pooled relative risks (pRR) = 1.11, 95%CI: 1.07-1.16)]}, while two strains significantly reduced the rate of antibiotic-associated diarrhea [S. boulardii I-745 (pRR = 0.47, 95%CI: 0.37-0.60) and Lactobacillus rhamnosus GG (pRR = 0.29, 95%CI: 0.17-0.48)]. None of the other four probiotic strains improved H. pylori therapy (C. butyricum, L. acidophilus, L. reuteri, L. casei).
Publish Date 2015-04-28 10:11
Citation McFarland LV, Malfertheiner P, Huang Y, Wang L. Meta-analysis of single strain probiotics for the eradication of Helicobacter pylori and prevention of adverse events. World J Meta-Anal 2015; 3(2): 97-117
Url http://www.wjgnet.com/2308-3840/full/v3/i2/97.htm
DOI http://dx.doi.org/10.13105/wjma.v3.i2.97
Full Article (PDF) WJMA-3-97.pdf
Full Article (Word) WJMA-3-97.doc
Manuscript File 14764-Review.docx
Answering Reviewers 14764-Answering reviewers.pdf
Biostatistics Review Certificate 14764-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 14764-Conflict-of-interest statement.pdf
Copyright License Agreement 14764-Copyright assignment.pdf
Data Sharing Statement 14764-Data sharing statement.pdf
Supplementary Material First pages of References with no DOI PMID.pdf
Peer-review Report 14764-Peer review(s).pdf
Scientific Misconduct Check 14764-CrossCheck.jpg
Scientific Editor Work List 14764-Scientific editor work list.pdf