BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/20/2015 5:01:00 PM | Browse: 924 | Download: 1442
 |
Received |
|
2014-10-27 08:04 |
|
Peer-Review Started |
|
2014-10-28 09:38 |
|
To Make the First Decision |
|
2014-11-14 18:50 |
|
Return for Revision |
|
2014-11-18 19:45 |
|
Revised |
|
2014-12-03 05:40 |
|
Second Decision |
|
2015-01-23 16:05 |
|
Accepted by Journal Editor-in-Chief |
|
2015-01-23 16:15 |
|
Accepted by Executive Editor-in-Chief |
|
2015-01-30 15:39 |
|
Articles in Press |
|
2015-01-30 18:32 |
 |
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2015-05-05 19:18 |
|
Publish the Manuscript Online |
|
2015-05-20 17:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Fecal stream diversion and mucosal cytokine levels in collagenous colitis: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Niki Daferera, Ashok Kumar Kumawat, Elisabeth Hultgren-Hörnquist, Simone Ignatova, Magnus Ström and Andreas Münch |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Andreas Münch, MD, PhD, Division of Gastroenterology and Hepatology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, 58185 Linköping, Sweden. andreas.munch@lio.se |
| Key Words |
Microscopic colitis; Collagenous colitis; Luminex; Mucosal cytokines; Fecal stream diversion |
| Core Tip |
The pathophysiology of collagenous colitis remains poorly understood. We describe a patient with chronic, active collagenous colitis who either failed to achieve clinical remission or experienced adverse effects with all medications given; therefore the patient was treated with a temporary loop ileostomy. We analyzed cytokine protein production with Luminex assays in colonic biopsy tissues obtained before and during fecal stream diversion (FSD) and after intestinal continuity was restored. Because FSD leads to clinical and histological remission, this study protocol provided a unique opportunity to study cytokine dynamics during different stages of disease. We were thus able to demonstrate that FSD was followed by a decrease in the levels of nearly all cytokines and that the restoration of bowel continuity increased the levels of the proinflammatory cytokines interleukin (IL)-2, IL-21 and IL-23. |
| Publish Date |
2015-05-20 17:01 |
| Citation |
Daferera N, Kumawat AK, Hultgren-Hörnquist E, Ignatova S, Ström M, Münch A. Fecal stream diversion and mucosal cytokine levels in collagenous colitis: A case report. World J Gastroenterol 2015; 21(19): 6065-6071 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i19/6065.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i19.6065 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
