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5/18/2015 5:02:00 PM | Browse: 1093 | Download: 2466
Publication Name World Journal of Gastroenterology
Manuscript ID 14869
Country China
Received
2014-10-29 14:08
Peer-Review Started
2014-10-29 19:00
To Make the First Decision
2014-11-26 18:20
Return for Revision
2014-12-04 16:44
Revised
2014-12-17 16:38
Second Decision
2015-01-28 14:08
Accepted by Journal Editor-in-Chief
2015-01-29 09:56
Accepted by Company Editor-in-Chief
2015-01-30 15:40
Articles in Press
2015-01-30 18:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-03-13 11:31
Typeset the Manuscript
2015-04-29 09:35
Publish the Manuscript Online
2015-05-18 17:02
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Models for predicting hepatitis B e antigen seroconversion in response to interferon-α in chronic hepatitis B patients
Manuscript Source Unsolicited Manuscript
All Author List Chang-Tai Wang, Ya-Fei Zhang, Bing-Hu Sun, Yu Dai, Hui-Lan Zhu, Yuan-Hong Xu, Meng-Ji Lu, Dong-Liang Yang, Xu Li and Zhen-Hua Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
Specialized Research Fund for the Doctoral Program of Higher Education of China 20093420120005
National Science Foundation of China 30771907
Corresponding Author Zhen-Hua Zhang, MD, PhD, Department of Infectious Diseases, the First Affiliated Hospital, Anhui Medical University, 218 Jixi Road, Hefei 230022, Anhui Province, China. zzh1974cn@163.com
Key Words Chronic hepatitis B; Interferon; Hepatitis B e antigen; Treatment; Model
Core Tip The response to interferon (IFN)-? therapy in chronic hepatitis B (CHB) patients varies significantly among individuals. This study of 147 patients evaluated multiple serological variables in hepatitis B e antigen (HBeAg)-positive CHB patients treated with IFN-?1b at baseline, 12 wk, and 24 wk, and then developed predictive models for HBeAg seroconversion at each of the 3 time points. The results suggest that models with good negative and positive predictive values were developed to calculate the probability of response to IFN-? therapy.
Publish Date 2015-05-18 17:02
Citation Wang CT, Zhang YF, Sun BH, Dai Y, Zhu HL, Xu YH, Lu MJ, Yang DL, Li X, Zhang ZH. Models for predicting hepatitis B e antigen seroconversion in response to interferon- in chronic hepatitis B patients. World J Gastroenterol 2015; 21(18): 5668-5676
URL http://www.wjgnet.com/1007-9327/full/v21/i18/5668.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i18.5668
Full Article (PDF) WJG-21-5668.pdf
Full Article (Word) WJG-21-5668.doc
Manuscript File 14869-Review.doc
Answering Reviewers 14869-Answering reviewers.pdf
Biostatistics Review Certificate 14869-Biostatistics statement.pdf
Clinical Trial Registration Statement 14869-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 14869-Conflict-of-interest statement.pdf
Copyright License Agreement 14869-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 14869-Clinical trial registration statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 14869-Institutional review boardstatement.pdf
Institutional Review Board Approval Form or Document 14869-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 14869-Language certificate.pdf
Peer-review Report 14869-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 14869-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check 14869-CrossCheck.jpg
Scientific Editor Work List 14869-Scientific editor work list.pdf