Publication Name	World Journal of Gastroenterology
Manuscript ID	1488
Country	China

Received	2012-12-14 21:16
Peer-Review Started	2012-12-17 15:52
To Make the First Decision	2012-12-28 17:54
Return for Revision	2012-12-30 21:40
Revised
Second Decision	2013-04-27 10:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-28 00:03
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-05-27 00:55
Typeset the Manuscript	2013-07-03 11:42
Publish the Manuscript Online	2013-07-13 17:01

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Autobiography
Article Title	Metabonomic studies of pancreatic cancer response to radiotherapy in a mouse xenograft model using magnetic resonance spectroscopy and principal components analysis
Manuscript Source	Invited Manuscript
All Author List	Xin-Hong He, Wen-Tao Li, Ya-Jia Gu, Bao-Feng Yang, Hui-Wen Deng, Yi-Hua Yu and Wei-Jun Peng
Funding Agency and Grant Number	Funding Agency Grant Number Medical Imageology Special Purpose Foundation of Cancer Hospital/Cancer Institute Fudan University YX200802
Corresponding Author	Wei-Jun Peng, MD, Department of Radiology, Fudan University Shanghai Cancer Center, No. 270, Dong'an Road, Shanghai 200032, China. weijunpeng378@gmail.com
Key Words	High-resolution magic angle spinning proton magnetic resonance spectroscopy; Principal components analysis; Pancreatic cancer; Radiotherapy
Core Tip	In the present study, for the first time to our knowledge, high-resolution magic angle spinning proton magnetic resonance spectroscopy and principal components analysis were combined to highlight metabolite profiles of pancreatic cancer after radiotherapy, by analyzing the correlation between radiotherapy effect and metabolic change, and optimizing the therapeutic scheme. The results showed that metabolic profile changes of pancreatic cancer after radiotherapy were closely correlated with therapeutic effect. The outcome of the study is both interesting and beneficial to pathological research, early diagnosis, and therapy evaluation of pancreatic diseases.
Publish Date	2013-07-13 17:01
Citation	He XH, Li WT, Gu YJ, Yang BF, Deng HW, Yu YH, Peng WJ. Metabonomic studies of pancreatic cancer response to radiotherapy in a mouse xenograft model using magnetic resonance spectroscopy and principal components analysis. World J Gastroenterol 2013; 19(26): 4200-4208
URL	http://www.wjgnet.com/1007-9327/full/v19/i26/4200.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i26.4200

Full Article (PDF)	WJG-19-4200.pdf
Manuscript File	1488-Review.doc
Answering Reviewers	1488-Answering reviewers.doc
Copyright License Agreement	1488-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	1488-Language certificate.pdf
Peer-review Report	1488-Peer review(s).pdf
Scientific Editor Work List	1488-Scientific editor work list.doc