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3/30/2015 5:46:00 PM | Browse: 843 | Download: 1495
Publication Name World Journal of Gastroenterology
Manuscript ID 14902
Country/Territory China
Received
2014-10-29 17:36
Peer-Review Started
2014-10-29 17:37
To Make the First Decision
2014-11-14 19:08
Return for Revision
2014-11-17 17:32
Revised
Second Decision
2015-01-06 13:39
Accepted by Journal Editor-in-Chief
2015-01-06 22:13
Accepted by Company Editor-in-Chief
2015-01-16 18:15
Articles in Press
2015-01-16 18:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-02-27 14:59
Typeset the Manuscript
2015-03-17 10:05
Publish the Manuscript Online
2015-03-30 14:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Research & Experimental Medicine
Manuscript Type Basic Study
Article Title Primary analysis and screening of microRNAs in gastric cancer side population cells
Manuscript Source Unsolicited Manuscript
All Author List Hai-Hong Zhang, Guo-Li Gu, Xiang-Yang Zhang, Feng-Zhi Li, Li Ding, Qin Fan, Ran Wu, Wei Shi, Xin-Yan Wang, Lin Chen, Xue-Ming Wei and Xiao-Ying Yuan
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81000706/H1108
National Key Technology Research and Development Program 2012BA141B01
Air Force General Hospital of Chinese PLA Innovation Fund KZ2013035
Corresponding Author Xue-Ming Wei, Professor, Department of General Surgery, Air Force General Hospital of Chinese PLA, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. 787939904@qq.com
Key Words ATP-binding cassette transporters; Side population cells; Benzimidazoles (Hoe 33342); Stomach neoplasm; Stem cells; MircoRNA
Core Tip MicroRNAs (miRNAs) act as one mechanism by which coding genes are regulated, and they are involved in many biological and pathological processes including carcinogenesis. However, identifying specific miRNAs is difficult, because many miRNAs possess more than one target and many target genes are regulated by more than one miRNA. We used fluorescence-activated cell sorting and Hoechst 33342 labeling to obtain side population (SP) cells from the human gastric carcinoma cell line MKN-45. The miRNA expression profiles of SP and major population cells were examined by miRNA gene chip analysis, and key miRNAs were identified according to aberrant expression and their possible targets as predicted by bioinformatics.
Publish Date 2015-03-30 14:23
Citation Zhang HH, Gu GL, Zhang XY, Li FZ, Ding L, Fan Q, Wu R, Shi W, Wang XY, Chen L, Wei XM, Yuan XY. Primary analysis and screening of microRNAs in gastric cancer side population cells. World J Gastroenterol 2015; 21(12): 3519-3526
URL http://www.wjgnet.com/1007-9327/full/v21/i12/3519.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i12.3519
Full Article (PDF) WJG-21-3519.pdf
Full Article (Word) WJG-21-3519.doc
Manuscript File 14902-Review.doc
Answering Reviewers 14902-Answering reviewers.pdf
Biostatistics Review Certificate 14902-Biostatistics.pdf
Conflict-of-Interest Disclosure Form 14902-Conflict-of-interest statement.pdf
Copyright License Agreement 14902-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 14902-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 14902-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 14902-Language certificate.pdf
Peer-review Report 14902-Peer-review(s).pdf
Scientific Misconduct Check 14902-CrossCheck.jpg
Scientific Editor Work List 14902-Scientific editor work list.pdf