| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Secondary acute promyelocytic leukemia following chemotherapy for gastric cancer: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying-Cheng Zhang, Yu-Qi Zhou, Bing Yan, Jun Shi, Li-Juan Xiu, Yu-Wei Sun, Xuan Liu, Zhi-Feng Qin, Pin-Kang Wei and Yong-Jin Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81173403 |
|
| Corresponding Author |
Yong-Jin Li, PhD, Department of Traditional Chinese Medicine, Changzheng Hospital of the Second Military Medical University, No. 415 Fengyang Road, Huangpu District, Shanghai 200003, China. yongjingli888@163.com |
| Key Words |
Gastric cancer; Acute promyelocytic leukemia; Oxaliplatin; Capecitabine; Chemotherapy |
| Core Tip |
In the current study, t-acute promyelocytic leukemia (t-APL) was likely induced by treatment with oxaliplatin, capecitabine and recombinant human granulocyte-colony stimulating factor. The gastric cancer patient, classified as clinical stage cT4N1M0, had a rare karyotype: 46,XY,t(15;17)(q22;q21)[15]/46,idem,-9,+add(9)(p22)[2]/46,XY[3]. This case demonstrates that certain cytotoxic agents can induce t-APL in gastric cancer. We recommend mandatory additional evaluation for patients undergoing this treatment regimen. |
| Publish Date |
2015-04-15 11:01 |
| Citation |
Zhang YC, Zhou YQ, Yan B, Shi J, Xiu LJ, Sun YW, Liu X, Qin ZF, Wei PK, Li YJ. Secondary acute promyelocytic leukemia following chemotherapy for gastric cancer: A case report. World J Gastroenterol 2015; 21(14): 4402-4407 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i14/4402.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i14.4402 |
