Publication Name	World Journal of Gastroenterology
Manuscript ID	14930
Country	China

Received	2014-10-31 09:09
Peer-Review Started	2014-10-31 13:45
To Make the First Decision	2014-11-26 18:20
Return for Revision	2014-12-04 17:08
Revised	2014-12-19 15:10
Second Decision	2015-01-16 09:56
Accepted by Journal Editor-in-Chief	2015-01-16 14:40
Accepted by Company Editor-in-Chief	2015-02-11 15:17
Articles in Press	2015-02-11 16:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-02-22 23:41
Typeset the Manuscript	2015-03-31 20:40
Publish the Manuscript Online	2015-04-15 11:01

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Case Control Study
Article Title	Interleukin-21 gene polymorphisms and chronic hepatitis B infection in a Chinese population
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Yan Yao, Kang Chao, Min-Rui Li, Yan-Qing Wu and Bi-Hui Zhong
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81170392
Corresponding Author	Bi-Hui Zhong, MD, PhD, Division of Gastroenterology, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan Road II, Guangzhou 510080, Guangdong Province, China. sophiazhong@medmail.com.cn
Key Words	Chinese population; Chronic hepatitis B virus infection; Interleukin-21 gene; rs13143866; rs2221903; rs907715; Single-nucleotide polymorphism
Core Tip	This study is the first to investigate the relationship between single nucleotide polymorphism rs13143866 of the interleukin-21 gene and chronic hepatitis B virus (HBV) infection in a Chinese population. We found that genotypes rs13143866 AA and rs2221903 TC were risk factors for carrying HBV, and the ATA haplotype (rs13143866, rs2221903 and rs907715) increased the risk of HBV-related hepatocellular carcinoma.
Publish Date	2015-04-15 11:01
Citation	Yao JY, Chao K, Li MR, Wu YQ, Zhong BH. Interleukin-21 gene polymorphisms and chronic hepatitis B infection in a Chinese population. World J Gastroenterol 2015; 21(14): 4232-4239
URL	http://www.wjgnet.com/1007-9327/full/v21/i14/4232.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i14.4232

Full Article (PDF)	WJG-21-4232.pdf
Full Article (Word)	WJG-21-4232.doc
Manuscript File	14930-Review.doc
Answering Reviewers	14930-Answering reviewers.pdf
Biostatistics Review Certificate	14930-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	14930-Conflict-of-interest statement.pdf
Copyright License Agreement	14930-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	14930-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	14930-Language certificate.PDF
Peer-review Report	14930-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	14930-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	14930-Scientific misconduct check.pdf
Scientific Editor Work List	14930-Scientific editor work list.pdf