Publication Name	World Journal of Nephrology
Manuscript ID	15022
Country	Greece

Received	2014-11-04 19:28
Peer-Review Started	2014-11-09 16:04
To Make the First Decision	2014-11-27 12:21
Return for Revision	2014-12-06 18:45
Revised	2014-12-22 18:48
Second Decision	2015-04-01 14:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-09 16:44
Articles in Press	2015-04-09 16:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-03 13:50
Publish the Manuscript Online	2015-07-06 18:45

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Randomized Clinical Trial
Article Title	Albuminuria as a marker of arterial stiffness in chronic kidney disease patients
Manuscript Source	Unsolicited Manuscript
All Author List	Rigas G Kalaitzidis, Despina P Karasavvidou, Athina Tatsioni, Kosmas Pappas, Giorgos Katatsis, Angelos Liontos and Moses S Elisaf
Funding Agency and Grant Number
Corresponding Author	Moses S Elisaf, MD, FASA, FRSH, Professor, Department of Internal Medicine, Medical School, University of Ioannina, Epirus, 45110 Ioannina, Greece. egepi@cc.uoi.gr
Key Words	Arterial stiffness; Pulse wave velocity; Augmentation index; Albuminuria
Core Tip	Albuminuria heightened cardiovascular disease risk. Pulse wave velocity and augmentation index are markers of aortic stiffness (AS). However, whether severely increased albuminuria is a factor of AS elevation and its progressive deterioration in non-diabetic hypertensive patients treated with renin angiotensin aldosterone blockade agents (RAAS) has not be studied. In this study we aimed to access the association between albuminuria levels and AS, in chronic kidney disease (CKD) stage 1-2 non-diabetic patients with hypertension. All patients were already treated with RAAS blockade agents. Our findings demonstrate an independent association between AS indices and severely increased albuminuria in non-diabetic, hypertensive patients with CKD stages 1-2 treated with RAAS blockers.
Publish Date	2015-07-06 18:45
Citation	Kalaitzidis RG, Karasavvidou DP, Tatsioni A, Pappas K, Katatsis G, Liontos A, Elisaf MS. Albuminuria as a marker of arterial stiffness in chronic kidney disease patients. World J Nephrol 2015; 4(3): 406-414
URL	http://www.wjgnet.com/2220-6124/full/v4/i3/406.htm
DOI	http://dx.doi.org/10.5527/wjn.v4.i3.406

Full Article (PDF)	WJN-4-406.pdf
Full Article (Word)	WJN-4-406.doc
Manuscript File	15022-Review.docx
Answering Reviewers	15022-Answering reviewers.pdf
Biostatistics Review Certificate	15022-Biostatistics statement.pdf
Clinical Trial Registration Statement	15022-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	15022-Conflict-of-interest statement.pdf
Copyright License Agreement	15022-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	15022-Clinical trial registration statement.pdf
Institutional Review Board Approval Form or Document	15022-Institutional review board statement.pdf
Peer-review Report	15022-Peer-review(s).pdf
Scientific Misconduct Check	15022-Scientific misconduct check.pdf
Scientific Editor Work List	15022-Scientific editor work list.pdf