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Articles Published Processes
4/15/2015 11:01:00 AM | Browse: 1246 | Download: 2204
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Received |
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2014-11-05 09:05 |
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Peer-Review Started |
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2014-11-05 13:56 |
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To Make the First Decision |
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2014-11-26 18:25 |
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Return for Revision |
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2014-11-28 14:03 |
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Revised |
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2014-12-20 21:54 |
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Second Decision |
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2015-01-20 09:33 |
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Accepted by Journal Editor-in-Chief |
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2015-01-21 03:08 |
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Accepted by Executive Editor-in-Chief |
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2015-01-30 15:27 |
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Articles in Press |
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2015-01-30 18:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-02-21 22:09 |
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Typeset the Manuscript |
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2015-04-01 09:18 |
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Publish the Manuscript Online |
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2015-04-15 11:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Control Study |
| Article Title |
Methyl-methanesulfonate sensitivity 19 expression is associated with metastasis and chemoradiotherapy response in esophageal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jin-Liang Zhang, Hui-Yun Wang, Qing Yang, Shi-Yong Lin, Guang-Yu Luo, Rong Zhang and Guo-Liang Xu |
| Funding Agency and Grant Number |
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| Corresponding Author |
Guo-Liang Xu, Professor, Department of Endoscopy and Laser, State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute, National Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, 651 Dongfeng East Road, East Building, Guangzhou 510060, Guangdong Province, China. xugl@sysucc.org.cn |
| Key Words |
Chemoradiotherapy; Esophageal squamous cell carcinoma; Metastases; Methyl-methanesulfonate sensitivity 19; Surgery |
| Core Tip |
Methyl-methanesulfonate sensitivity 19 (MMS19) was first identified as a DNA repair protein, and recently as a part of cytoplasmic Fe-S assembly machinery that produce proteins involved in maintenance of genomic stability, such as DNA polymerase, DNA repair proteins, and DNA nuclease/helicase. However, the clinical significance of MMS19 protein expression in esophageal cancer has not been reported. This study shows that MMS19 is abnormally expressed in esophageal cancer, and the elevated cytoplasmic MMS19 expression is associated with lymph node and distant metastases, and response to chemoradiotherapy in esophageal squamous cell carcinoma. |
| Publish Date |
2015-04-15 11:01 |
| Citation |
Zhang JL, Wang HY, Yang Q, Lin SY, Luo GY, Zhang R, Xu GL. Methyl-methanesulfonate sensitivity 19 expression is associated with metastasis and chemoradiotherapy response in esophageal cancer. World J Gastroenterol 2015; 21(14): 4240-4247 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i14/4240.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i14.4240 |
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