Publication Name	World Journal of Methodology
Manuscript ID	15051
Country	Netherlands

Received	2014-11-06 08:46
Peer-Review Started	2014-11-06 13:51
To Make the First Decision	2015-01-20 13:39
Return for Revision	2015-02-03 10:56
Revised	2015-02-10 18:58
Second Decision	2015-05-15 17:37
Accepted by Journal Editor-in-Chief	2015-05-15 18:05
Accepted by Executive Editor-in-Chief	2015-05-27 15:05
Articles in Press	2015-05-27 15:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-11 19:09
Publish the Manuscript Online	2015-07-07 20:52

ISSN	2222-0682 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Methodology
Manuscript Type	Diagnostic Advances
Article Title	Accurate diagnosis of myalgic encephalomyelitis and chronic fatigue syndrome based upon objective test methods for characteristic symptoms
Manuscript Source	Invited Manuscript
All Author List	Frank NM Twisk
Funding Agency and Grant Number
Corresponding Author	Frank NM Twisk, MBA, BEd, BEc, ME-de-patiënten Foundation, Zonnedauw 15, 1906 HB Limmen, The Netherlands. frank.twisk@hetnet.nl
Key Words	Myalgic encephalomyelitis; Chronic fatigue syndrome; Symptoms; Diagnosis; Disability; Impact
Core Tip	The diagnostic criteria for myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) define two distinct clinical entities. Cognitive impairment and post-exertional “malaise” (a long-lasting aggravation of typical symptoms, e.g., muscle weakness and cognitive “brain fog”, after minor exertion) are obligatory for the diagnosis ME, while chronic fatigue is the only mandatory symptom for the diagnosis CFS. There is debate about the nature and severity of the symptoms in ME and CFS. For clinical and research purposes it is essential to accurately diagnose patients using objective tests for characteristic symptoms if possible. This article reviews accepted methods to assess various distinctive symptoms of ME and CFS.
Publish Date	2015-07-07 20:52
Citation	Twisk FNM. Accurate diagnosis of myalgic encephalomyelitis and chronic fatigue syndrome based upon objective test methods for characteristic symptoms. World J Methodol 2015; 5(2): 68-87
URL	http://www.wjgnet.com/2222-0682/full/v5/i2/68.htm
DOI	http://dx.doi.org/10.5662/wjm.v5.i2.68

Full Article (PDF)	WJM-5-68.pdf
Full Article (Word)	WJM-5-68.doc
Manuscript File	15051-Review.docx
Answering Reviewers	15051-Answering reviewers.pdf
Audio Core Tip	15051-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15051-Conflict-of-interest statement.pdf
Copyright License Agreement	15051-Copyright assignment.pdf
Peer-review Report	15051-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15051-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15051-Scientific misconduct check.pdf
Scientific Editor Work List	15051-Scientific editor work list.pdf