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Articles Published Processes
4/27/2015 4:29:00 PM | Browse: 1100 | Download: 2769
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Received |
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2014-11-08 12:30 |
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Peer-Review Started |
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2014-11-08 21:52 |
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To Make the First Decision |
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2014-12-11 20:23 |
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Return for Revision |
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2014-12-15 17:34 |
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Revised |
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2015-01-01 01:06 |
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Second Decision |
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2015-01-23 17:08 |
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Accepted by Journal Editor-in-Chief |
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2015-01-23 17:18 |
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Accepted by Executive Editor-in-Chief |
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2015-01-30 15:29 |
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Articles in Press |
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2015-01-30 18:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-03-05 17:39 |
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Typeset the Manuscript |
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2015-04-14 15:56 |
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Publish the Manuscript Online |
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2015-04-27 16:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Toxoplasma gondii causes death and plastic alteration in the jejunal myenteric plexus
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Eduardo José de Almeida Araújo, Larissa Marchi Zaniolo, Suellen Laís Vicentino, Marcelo Biondaro Góis, Jacqueline Nelisis Zanoni, Aristeu Vieira da Silva and Débora de Mello Gonçales Sant’Ana |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Eduardo José de Almeida Araújo, Departamento de Histologia, Centro de Ciências Biológicas, Universidade Estadual de Londrina, PO 10.011, 86057-970 Paraná, Brazil. eduardoaraujo@uel.br |
| Key Words |
Enteric nervous system; Infectious diseases; Glial cells; Nitric oxide; Neuronal plasticity; Small intestine; Toxoplasmosis; Vasoactive intestinal peptide |
| Core Tip |
The authors assessed the effects of ME-49 Toxoplasma gondii (T. gondii) strain infection on the myenteric plexus and external muscle of the jejunum in rats. They found an uncommon result when T. gondii infection was evaluated in rats: death of myenteric neurons and enteric glial cells. In addition, the remaining neurons showed hypertrophy and the number of nitrergic neurons increased. These alterations were possibly responsible for hypertrophy of the external muscle observed in the jejunal wall. The strain (ME-49) and the life form (oocysts) of T. gondii used here were the determinants of all these findings. |
| Publish Date |
2015-04-27 16:22 |
| Citation |
Araújo EJA, Zaniolo LM, Vicentino SL, Góis MB, Zanoni JN, da Silva AV, Sant’Ana DMG. Toxoplasma gondii causes death and plastic alteration in the jejunal myenteric plexus. World J Gastroenterol 2015; 21(16): 4829-4839 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i16/4829.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i16.4829 |
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