Publication Name	World Journal of Virology
Manuscript ID	15114
Country	Italy

Received	2014-11-10 09:13
Peer-Review Started	2014-11-10 18:07
To Make the First Decision	2014-12-26 13:18
Return for Revision	2015-01-01 16:33
Revised	2015-01-20 00:01
Second Decision	2015-02-10 16:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-02-12 14:27
Articles in Press	2015-02-12 14:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-17 17:25
Publish the Manuscript Online	2015-04-30 17:58

ISSN	2220-3249 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Minireviews
Article Title	Key role of human leukocyte antigen in modulating human immunodeficiency virus progression: An overview of the possible applications
Manuscript Source	Invited Manuscript
All Author List	Alba Grifoni, Carla Montesano, Vittorio Colizzi and Massimo Amicosante
Funding Agency and Grant Number
Corresponding Author	Massimo Amicosante, PhD, Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Via Montpellier 1, 00133 Rome, Italy. amicosan@uniroma2.it
Key Words	Human immunodeficiency virus progression; Human leukocyte antigen; Epitope; Immunoinformatics; CD8+ T lymphocytes
Core Tip	Human immunodeficiency virus (HIV) disease progression depends on several host factors. Among them human leukocyte antigen (HLA) locus has a main role due to the peculiar capability to modulate both innate and adaptive immune response. In this review, the role of HLA molecules and its receptors in HIV progression toward acquired immunodeficiency disease syndrome is summarized. A better knowledge about HLA-peptide presentation and recognition by immune cells will open new applications in HIV vaccine and diagnostics design.
Publish Date	2015-04-30 17:58
Citation	Grifoni A, Montesano C, Colizzi V, Amicosante M. Key role of human leukocyte antigen in modulating human immunodeficiency virus progression: An overview of the possible applications. World J Virol 2015; 4(2): 124-133
URL	http://www.wjgnet.com/2220-3249/full/v4/i2/124.htm
DOI	http://dx.doi.org/10.5501/wjv.v4.i2.124

Full Article (PDF)	WJV-4-124.pdf
Full Article (Word)	WJV-4-124.doc
Manuscript File	15114-Review.doc
Answering Reviewers	15114-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	15114-Conflict-of-interest statement.pdf
Copyright License Agreement	15114-Copyright assignment.pdf
Peer-review Report	15114-Peer-review(s).pdf
Scientific Misconduct Check	15114-Scientific misconduct check.pdf
Scientific Editor Work List	15114-Scientific editor work list.pdf