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Articles Published Processes
12/2/2015 11:59:00 AM | Browse: 1159 | Download: 1641
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Received |
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2014-11-11 10:00 |
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Peer-Review Started |
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2014-11-11 16:33 |
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To Make the First Decision |
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2014-12-26 13:13 |
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Return for Revision |
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2014-12-31 08:22 |
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Revised |
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2015-01-12 20:07 |
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Second Decision |
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2015-02-03 19:43 |
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Accepted by Journal Editor-in-Chief |
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2015-02-06 16:23 |
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Accepted by Executive Editor-in-Chief |
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2015-02-11 15:57 |
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Articles in Press |
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2015-02-11 15:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-04-13 14:14 |
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Publish the Manuscript Online |
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2015-05-15 19:54 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Minireviews |
Article Title |
Adipose tissue fibrosis
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Manuscript Source |
Invited Manuscript |
All Author List |
Christa Buechler, Sabrina Krautbauer and Kristina Eisinger |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
German Research Foundation |
BU 1141/8-1 |
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Corresponding Author |
Christa Buechler, PhD, Department of Internal Medicine I, University Hospital of Regensburg, Franz-Josef-Strauß-Allee 11, 93042 Regensburg,
Germany. christa.buechler@klinik.uni-regensburg.de
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Key Words |
Collagen; Hypoxia; Insulin resistance; Immune cells; Adipocyte |
Core Tip |
The close association of adipose tissue fibro-sis and metabolic complications in obesity has been corroborated in rodent and human studies. Adipo-se tis-sue hypoxia initiates fibrosis which is further aggravated by inflammation. In adipose tissue preadi-pocytes, adipocytes and resident macrophages produce collagen showing that the fibrotic process differs from the extensively studied scar formation in the liver. Strategies to resolve fibrosis in fat tissues thereby promoting healthy adipose tissue growth are suggested to improve metabolic situation in obese patients.
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Publish Date |
2015-05-15 19:54 |
Citation |
Buechler C, Krautbauer S, Eisinger K. Adipose tissue fibrosis. World J Diabetes 2015; 6(4): 548-553 |
URL |
http://www.wjgnet.com/1948-9358/full/v6/i4/548.htm |
DOI |
http://dx.doi.org/10.4239/wjd.v6.i4.548 |
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