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Articles Published Processes
12/2/2015 11:57:00 AM | Browse: 1179 | Download: 1993
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Received |
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2014-11-13 09:08 |
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Peer-Review Started |
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2014-11-13 19:22 |
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To Make the First Decision |
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2014-12-26 13:13 |
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Return for Revision |
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2014-12-31 08:51 |
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Revised |
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2015-02-05 17:18 |
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Second Decision |
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2015-02-27 09:36 |
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Accepted by Journal Editor-in-Chief |
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2015-02-27 12:37 |
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Accepted by Executive Editor-in-Chief |
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2015-03-09 17:24 |
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Articles in Press |
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2015-03-09 17:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-05-15 14:27 |
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Publish the Manuscript Online |
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2015-05-31 19:16 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Basic Study |
Article Title |
Fetal kidney stem cells ameliorate cisplatin induced acute renal failure and promote renal angiogenesis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ashwani Kumar Gupta, Sachin H Jadhav, Naresh Kumar Tripathy and Soniya Nityanand |
Funding Agency and Grant Number |
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Corresponding Author |
Dr. Soniya Nityanand, MD, PhD, FNASc, FASc, Professor and Head, Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Rae Bareli Road, Lucknow 226014, India. soniya_nityanand@yahoo.co.in
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Key Words |
Fetal kidney stem cells; Mesenchymal and renal progenitor markers; Acute renal failure; Stem cell therapy; Angiogenesis |
Core Tip |
This study provides novel data on the thera-peutic effect of culture expanded fetal kidney stem cells (fKSC) in acute renal failure (ARF). The fKSC represent primitive renal stem cells that express mesenchymal and renal progenitor markers. They exhibit in vitro angiogenesis and potential to differentiate into renal epithelial cells. On administration in ARF rats, they rapidly improve renal function and histology. The therapeutic effects of fKSC are accompanied with increased capillary density in kidney tissues suggesting that induction of renal angiogenesis may be an important therapeutic mechanism of these stem cells.
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Publish Date |
2015-05-31 19:16 |
Citation |
Gupta AK, Jadhav SH, Tripathy NK, Nityanand S. Fetal kidney stem cells ameliorate cisplatin induced acute renal failure and promote renal angiogenesis. World J Stem Cells 2015; 7(4): 776-788 |
URL |
http://www.wjgnet.com/1948-0210/full/v7/i4/776.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v7.i4.776 |
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