Publication Name	World Journal of Nephrology
Manuscript ID	15285
Country	Canada

Received	2014-11-19 17:06
Peer-Review Started	2014-11-22 10:59
To Make the First Decision	2014-12-12 17:23
Return for Revision	2014-12-19 17:40
Revised	2015-01-03 05:32
Second Decision	2015-09-21 17:10
Accepted by Journal Editor-in-Chief	2015-09-21 18:37
Accepted by Executive Editor-in-Chief	2015-09-30 18:12
Articles in Press	2015-09-30 18:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-27 11:30
Publish the Manuscript Online	2015-11-12 11:30

ISSN	2220-6124 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Hematology
Manuscript Type	Case Report
Article Title	Lupus-associated thrombotic thrombocytopenic purpura-like microangiopathy
Manuscript Source	Unsolicited Manuscript
All Author List	Daniel Blum and Geoffrey Blake
Funding Agency and Grant Number
Corresponding Author	Daniel Blum, MDCM, Department of Internal Medicine (G-050), Jewish General Hospital, 3755 Cote Saint Catherine, Montreal, Quebec H3T1E2, Canada. daniel.blum@mail.mcgill.ca
Key Words	Microangiopathic hemolytic anemia; Micro­angiopathy; Thrombotic thrombocytopenic purpura; Atypical hemolytic-uremic syndrome; Hemolytic uremic syndrome; Systemic lupus erythematosus associated thrombotic thrombocytopenic purpura-like microan­giopathic hemolytic anemia; Lupus nephritis; Lupus; Plasma exchange
Core Tip	In patients with lupus who develop thrombotic microangiopathy, early initiation of plasma exchange appears to carry a survival benefit - even in those patients whose ADAMTS13 activity levels are not severely deficient. This improved survival has become apparent in the last ten years during which time seven cases of thrombotic microangiopathy complicating lupus and treated with plasma exchange have been reported. The present article describes the eighth such case, reviews the previously described cases and outcomes of microangiopathy in lupus, and hypothesizes as to why plasma exchange appears to be beneficial in this subset of patients with atypical haemolytic uremic syndrome.
Publish Date	2015-11-12 11:30
Citation	Blum D, Blake G. Lupus-associated thrombotic thrombo­cytopenic purpura-like microangiopathy. World J Nephrol 2015; 4(5): 528-531
URL	http://www.wjgnet.com/2220-6124/full/v4/i5/528.htm
DOI	http://dx.doi.org/10.5527/wjn.v4.i5.528

Full Article (PDF)	WJN-4-528.pdf
Full Article (Word)	WJN-4-528.doc
Manuscript File	15285-Review.docx
Answering Reviewers	15285-Answering reviewers.pdf
Audio Core Tip	15285-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15285-Conflict-of-interest statement.pdf
Copyright License Agreement	15285-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	15285-Institutional review board statement.pdf
Peer-review Report	15285-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15285-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15285-Scientific misconduct check.pdf
Scientific Editor Work List	15285-Scientific editor work list.pdf