Publication Name	World Journal of Diabetes
Manuscript ID	15315
Country	Palestine

Received	2014-11-21 08:26
Peer-Review Started	2014-11-23 20:24
To Make the First Decision	2015-02-07 15:01
Return for Revision	2015-02-11 10:27
Revised	2015-03-13 06:44
Second Decision	2015-04-01 15:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-14 16:39
Articles in Press	2015-04-14 16:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-08 17:17
Publish the Manuscript Online	2015-06-20 17:24

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Review
Article Title	Diabetes mellitus: The epidemic of the century
Manuscript Source	Invited Manuscript
All Author List	Akram T Kharroubi and Hisham M Darwish
Funding Agency and Grant Number
Corresponding Author	Akram T Kharroubi, PhD, Associate Professor of Biochemistry and Endocrinology, Dean of Faculty of Health Professions, Department of Medical Laboratory Sciences, Faculty of Health Professions, Al-Quds University, P.O. Box 51000, Abed Elhamaid Shoman Street, Beit Hanina-Jerusalem, Jerusalem 91000, Palestine. akram.kharroubi@gmail.com
Key Words	Diabetes; Classification of diabetes; Type 1 diabetes; Type 2 diabetes; Gestational diabetes; Diagnosis; Etiology; Genetics
Core Tip	Diabetes mellitus is rising to an alarming epidemic level. Early diagnosis of diabetes and prediabetes is essential using recommended hemoglobin A1c criteria for different types except for gestational diabetes. Screening for diabetes especially in underdeveloped countries is essential to reduce late diagnosis. Diabetes development involves the interaction between genetic and non-genetic factors. Biomedical research continues to provide new insights in our understanding of the mechanism of diabetes development that is reviewed here. Recent studies may provide tools for the use of several genes as targets for risk assessment, therapeutic strategies and prediction of complications.
Publish Date	2015-06-20 17:24
Citation	Kharroubi AT, Darwish HM. Diabetes mellitus: The epidemic of the century. World J Diabetes 2015; 6(6): 850-867
URL	http://www.wjgnet.com/1948-9358/full/v6/i6/850.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i6.850

Full Article (PDF)	WJD-6-850.pdf
Full Article (Word)	WJD-6-850.doc
Manuscript File	15315-Review.docx
Answering Reviewers	15315-Answering reviewers.pdf
Audio Core Tip	15315-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15315-Conflict-of-interest statement.pdf
Copyright License Agreement	15315-Copyright assignment.pdf
Peer-review Report	15315-Peer-review(s).pdf
Scientific Misconduct Check	15315-Scientific misconduct check.pdf
Scientific Editor Work List	15315-Scientific editor work list.pdf