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Articles Published Processes
12/10/2015 10:35:00 AM | Browse: 1324 | Download: 1593
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Received |
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2014-11-22 15:04 |
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Peer-Review Started |
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2014-11-23 16:30 |
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To Make the First Decision |
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2014-12-26 13:30 |
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Return for Revision |
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2015-01-05 17:10 |
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Revised |
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2015-01-16 00:00 |
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Second Decision |
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2015-02-10 21:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-02-11 15:50 |
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Articles in Press |
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2015-02-11 16:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-03-08 19:07 |
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Publish the Manuscript Online |
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2015-03-19 16:57 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Biomarkers in nonalcoholic fatty liver disease-the emperor has no clothes?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Madhusudana Girija Sanal |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| IIP fellowship (2013-2014), Albert Einstein College of Medicine, New York, through the generosity of the Gruss Lipper Family Foundation |
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| Corresponding Author |
Madhusudana Girija Sanal, MD, PhD, IIP Research Fellow, Albert Einstein College of Medicine, Room#323, Ullmann Building, 1300 Morris Park Avenue, Bronx, NY 10461, United States. sanalmg@gmail.com |
| Key Words |
Nonalcoholic fatty liver disease; Biomarkers; Fibrosis; Cirrhosis; Steatohepatitis; Liver biopsy |
| Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is not a single disease, but encompasses a spectrum of diseases and this makes it very difficult to find highly specific and sensitive biomarkers. We should therefore aim to find relevant prognostic markers rather than accurate diagnostic markers which will help to minimize the frequency of liver biopsies to evaluate disease progression. There is no evidence that biopsy and detailed staging of NAFLD is important in the NAFLD management and benefits patients. Finally, there is no evidence based treatment for NAFLD other than management of 'metabolic syndrome' by pharmacological or non-pharmacological (lifestyle management/surgical) approaches. |
| Publish Date |
2015-03-19 16:57 |
| Citation |
Sanal MG. Biomarkers in nonalcoholic fatty liver disease-the emperor has no clothes? World J Gastroenterol 2015; 21(11): 3223-3231 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i11/3223.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i11.3223 |
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