Publication Name	World Journal of Pharmacology
Manuscript ID	15353
Country	India

Received	2014-11-23 13:14
Peer-Review Started	2014-11-23 19:37
To Make the First Decision	2014-12-12 17:22
Return for Revision	2014-12-29 15:49
Revised	2015-05-29 00:00
Second Decision	2015-08-03 15:04
Accepted by Journal Editor-in-Chief	2015-08-06 17:52
Accepted by Company Editor-in-Chief	2015-08-11 15:06
Articles in Press	2015-08-11 15:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-31 13:48
Publish the Manuscript Online	2015-09-08 17:41

ISSN	2220-3192 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Review
Article Title	Therapeutic targets and delivery challenges for Alzheimer’s disease
Manuscript Source	Invited Manuscript
All Author List	Preshita Desai, Harshad Shete, Rahul Adnaik, John Disouza and Vandana Patravale
Funding Agency and Grant Number
Corresponding Author	Vandana Patravale, PhD, Professor of Pharmaceutics, Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga (East), Mumbai 400019, Maharashtra, India. vbp_muict@yahoo.co.in
Key Words	Neurofibrillary tangles; Alzheimer’s disease; Dementia; Amyloid ; Tau; Neurodegeneration; Blood brain barrier; Transdermal; Nasal
Core Tip	Dementia, including Alzheimer’s disease, the 21st Century epidemic, is one of the most significant social and health crises which has currently afflicted nearly 44 million patients worldwide and is on rampant rise. This portrays the unmet need towards better understanding of Alzheimer’s disease pathomechanisms and related research towards more effective treatment strategies. The review thus focuses on thorough understanding of Alzheimer’s disease pathophysiology, pharmacotherapy in terms of explored therapeutic targets and drug delivery systems towards better delivery of anti-Alzheirmer actives and a possible way ahead.
Publish Date	2015-09-08 17:41
Citation	Desai P, Shete H, Adnaik R, Disouza J, Patravale V. Therapeutic targets and delivery challenges for Alzheimer’s disease. World J Pharmacol 2015; 4(3): 236-264
URL	http://www.wjgnet.com/2220-3192/full/v4/i3/236.htm
DOI	http://dx.doi.org/10.5497/wjp.v4.i3.236

Full Article (PDF)	WJP-4-236.pdf
Full Article (Word)	WJP-4-236.doc
Manuscript File	15353-Review.docx
Answering Reviewers	15353-Answering reviewers.pdf
Audio Core Tip	15353-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15353-Conflict-of-interest statement.pdf
Copyright License Agreement	15353-Copyright assignment.pdf
Peer-review Report	15353-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15353-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15353-Scientific misconduct check.pdf
Scientific Editor Work List	15353-Scientific editor work list.pdf