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5/30/2015 1:35:00 PM | Browse: 1149 | Download: 1894
Publication Name World Journal of Gastroenterology
Manuscript ID 15402
Country China
Received
2014-11-25 20:08
Peer-Review Started
2014-11-26 10:24
To Make the First Decision
2015-01-22 16:44
Return for Revision
2015-01-30 16:48
Revised
2015-02-10 16:30
Second Decision
2015-03-04 18:25
Accepted by Journal Editor-in-Chief
2015-03-05 12:31
Accepted by Company Editor-in-Chief
2015-03-12 16:22
Articles in Press
2015-03-12 16:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-03-31 09:47
Typeset the Manuscript
2015-05-18 10:47
Publish the Manuscript Online
2015-05-30 13:32
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Peng Wang, Qiao Shi, Wen-Hong Deng, Jia Yu, Teng Zuo, Fang-Chao Mei and Wei-Xing Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81370562
Corresponding Author Wei-Xing Wang, MD, Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, Hubei Province, China. sate.llite@163.com
Key Words NADPH oxidase 2; Macrophages; Vascular endothelial growth factor; Epidermal growth factor receptor; Prognosis; Survival time
Core Tip In this article, the authors used immunohistochemistry to analyze the expression of nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) in formalin-fixed paraffin-embedded tissues from 123 gastric cancer patients. Western blot analysis was employed to examine NOX2 expression in tumor and adjacent tissues. NOX2 was up-regulated in tumor tissues. NOX2 was positively correlated with vascular endothelial growth factor and epidermal growth factor receptor. The results also showed that patients who were NOX2 positive clearly presented worse outcomes than NOX2-negative patients. The expression of NOX2 could be used as a prognostic biomarker for gastric cancer.
Publish Date 2015-05-30 13:32
Citation Wang P, Shi Q, Deng WH, Yu J, Zuo T, Mei FC, Wang WX. Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancer. World J Gastroenterol 2015; 21(20): 6271-6279
URL http://www.wjgnet.com/1007-9327/full/v21/i20/6271.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i20.6271
Full Article (PDF) WJG-21-6271.pdf
Full Article (Word) WJG-21-6271.doc
Manuscript File 15402-Review.docx
Answering Reviewers 15402-Answering reviewers.pdf
Audio Core Tip 15402-Audio core tip.mp3
Biostatistics Review Certificate 15402-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 15402-Conflict-of-interest statement.pdf
Copyright License Agreement 15402-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 15402-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 15402-Language certificate.pdf
Peer-review Report 15402-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 15402-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 15402-Scientific misconduct check.pdf
Scientific Editor Work List 15402-Scientific editor work list.pdf