Publication Name	World Journal of Gastroenterology
Manuscript ID	15414
Country	Japan

Received	2014-11-26 09:22
Peer-Review Started	2014-11-26 09:54
To Make the First Decision	2014-12-26 13:24
Return for Revision	2014-12-31 09:09
Revised	2015-01-08 19:44
Second Decision	2015-01-19 16:33
Accepted by Journal Editor-in-Chief	2015-01-19 19:36
Accepted by Executive Editor-in-Chief	2015-01-21 17:11
Articles in Press	2015-01-21 17:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-28 15:57
Publish the Manuscript Online	2015-02-11 17:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Editorial
Article Title	Gut microbiota and liver diseases
Manuscript Source	Invited Manuscript
All Author List	Masami Minemura and Yukihiro Shimizu
Funding Agency and Grant Number
Corresponding Author	Yukihiro Shimizu, MD, PhD, Gastroenterology Center, Nanto Municipal Hospital, 936 Inami, Nanto, Toyama 932-0211, Japan. rsf14240@nifty.com
Key Words	Gut microbiota; Immune system; Liver disease; Metabolites; Non-alcoholic fatty liver disease; Hepatic encephalopathy
Core Tip	Gut microbiota are associated with various human diseases (e.g., metabolic, gastroenterological and liver diseases, and allergies). Genomic analyses of gut microbiota have enabled the comprehensive identification of the population of gut bacteria and revealed that changes in these populations are involved in various diseases’ pathophysiology. The liver is affected by changes in the intestinal milieu due to the entry of gut bacteria or their metabolites into the liver through the portal vein. Here we summarize the current understanding of changes in gut microbiota associated with various liver diseases. We also summarize the recent therapeutic trials of probiotics in liver diseases.
Publish Date	2015-02-11 17:56
Citation	Minemura M, Shimizu Y. Gut microbiota and liver diseases. World J Gastroenterol 2015; 21(6): 1691-1702
URL	http://www.wjgnet.com/1007-9327/full/v21/i6/1691.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i6.1691

Full Article (PDF)	WJG-21-1691.pdf
Full Article (Word)	WJG-21-1691.doc
Manuscript File	15414-Review.docx
Answering Reviewers	15414-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	15414-Conflict-of interest statement.pdf
Copyright License Agreement	15414-Copyrright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20141125202225.pdf
Peer-review Report	15414-Peer-review(s).pdf
Scientific Misconduct Check	15414-CorssCheck.jpg
Scientific Editor Work List	15414-Scientific editor work list.pdf