Publication Name	World Journal of Stem Cells
Manuscript ID	15433
Country	United States

Received	2014-11-27 10:27
Peer-Review Started	2014-11-29 12:34
To Make the First Decision	2014-12-26 13:17
Return for Revision	2015-01-01 14:12
Revised	2015-01-14 08:32
Second Decision	2015-07-06 08:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-07-17 14:25
Articles in Press	2015-07-17 14:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-09 12:00
Publish the Manuscript Online	2015-09-25 17:30

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Autologous tissue patch rich in stem cells created in the subcutaneous tissue
Manuscript Source	Invited Manuscript
All Author List	Ignacio Garcia-Gomez, Krishnamurthy P Gudehithlu, Jose A L Arruda and Ashok K Singh
Funding Agency and Grant Number
Corresponding Author	Ashok K Singh, PhD, John H. Stroger, Jr. Hospital of Cook County, 1969 West Ogden Avenue, Chicago, IL 60612, United States. singhashok100@yahoo.com
Key Words	Autologous tissue patch; Foreign body; Subcutaneous implantation; Mesenchymal stem cells; CD271; CD34
Core Tip	While much progress has been made in man-made tissue patches for organ repair, their clinical success has been bogged down by their inability to get promptly vascularized in vivo. We describe a methodology for creating tissue patches of several possible shapes/sizes in the subcutaneous tissue utilizing the foreign body reaction. These patches are endowed with a rich capillary network, abundant mesenchymal stem cells, and other accessory cells that support the viability of the tissue. Such in vivo generated patches for tissue repair promise to be safer, more readily vascularized, and stable for longer period in the body.
Publish Date	2015-09-25 17:30
Citation	Garcia-Gomez I, Gudehithlu KP, Arruda JAL, Singh AK. Autologous tissue patch rich in stem cells created in the subcutaneous tissue. World J Stem Cells 2015; 7(8): 1127-1136
URL	http://www.wjgnet.com/1948-0210/full/v7/i8/1127.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i8.1127

Full Article (PDF)	WJSC-7-1127.pdf
Full Article (Word)	WJSC-7-1127.doc
Manuscript File	15433-Review.doc
Answering Reviewers	15433-Answering reviewers.pdf
Audio Core Tip	15433-Audio core tip.m4a
Biostatistics Review Certificate	15433-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	15433-Conflict-of-interest statement.pdf
Copyright License Agreement	15433-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	15433-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	15433-Institutional review board statement.pdf
Peer-review Report	15433-Peer-review(s).pdf
Scientific Misconduct Check	15433-Scientific misconduct check.pdf
Scientific Editor Work List	15433-Scientific editor work list.pdf