Publication Name	World Journal of Gastroenterology
Manuscript ID	15481
Country	China

Received	2014-11-27 19:03
Peer-Review Started	2014-11-28 08:38
To Make the First Decision	2015-01-08 16:55
Return for Revision	2015-01-13 08:43
Revised	2015-01-21 08:11
Second Decision	2015-02-11 22:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-02-13 10:32
Articles in Press	2015-02-13 11:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-03-01 16:23
Typeset the Manuscript	2015-03-24 11:06
Publish the Manuscript Online	2015-04-07 17:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Virology
Manuscript Type	Topic Highlights
Article Title	Hepatitis C virus and antiviral innate immunity: Who wins at tug-of-war?
Manuscript Source	Invited Manuscript
All Author List	Da-Rong Yang and Hai-Zhen Zhu
Funding Agency and Grant Number
Corresponding Author	Hai-Zhen Zhu, Department of Molecular Medicine of College of Biology, State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Yuelushan, Changsha 410082, Hunan Province, China. zhuhaizhen69@yahoo.com
Key Words	Hepatitis C virus; Interferon; Interferon-stimulated gene; RIG-I; Toll-like receptor; Virus-host interaction; Chronic hepatitis; Immune evasion; Cell culture system for hepatitis C virus
Core Tip	The complex interaction between hepatitis C virus (HCV) and its host determines which side the balance tends to be tipped between antiviral innate response and viral immune evasion. The development of new cell culture systems and small animal models for HCV research permits increased understanding of how the host responds to viral infection and what leads to HCV evasion of innate immunity. Recent discoveries in these areas reveal many pivotal factors imparting the control of viral-induced innate immunity, and facilitate the development of novel drugs and effective vaccines for HCV infection.
Publish Date	2015-04-07 17:13
Citation	Yang DR, Zhu HZ. Hepatitis C virus and antiviral innate immunity: Who wins at tug-of-war? World J Gastroenterol 2015; 21(13): 3786-3800
URL	http://www.wjgnet.com/1007-9327/full/v21/i13/3786.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i13.3786

Full Article (PDF)	WJG-21-3786.pdf
Full Article (Word)	WJG-21-3786.doc
Manuscript File	15481-Review.doc
Answering Reviewers	15481-Answering reviewers.pdf
Audio Core Tip	15481-Audio core tip.mp3
Copyright License Agreement	15481-Copyright assignment.pdf
Peer-review Report	15481-Peer-review(s).pdf
Scientific Misconduct Check	15481-Scientific misconduct check.pdf
Scientific Editor Work List	15481-Scientific editor work list.pdf