Publication Name	World Journal of Gastroenterology
Manuscript ID	15513
Country	China

Received	2014-12-01 10:05
Peer-Review Started	2014-12-03 19:15
To Make the First Decision	2014-12-26 13:22
Return for Revision	2014-12-31 09:15
Revised	2015-01-19 10:29
Second Decision	2015-02-11 22:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-02-13 10:34
Articles in Press	2015-02-13 11:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-04-07 11:23
Typeset the Manuscript	2015-05-08 17:23
Publish the Manuscript Online	2015-06-18 17:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Assessment of liver fibrosis by Fibroscan as compared to liver biopsy in biliary atresia
Manuscript Source	Unsolicited Manuscript
All Author List	Qiu-Long Shen, Ya-Jun Chen, Zeng-Meng Wang, Ting-Chong Zhang, Wen-Bo Pang, Jun Shu and Chun-Hui Peng
Funding Agency and Grant Number
Corresponding Author	Ya-Jun Chen, MD, PHD, Department of Pediatric General Surgery, Beijing Children’s Hospital, Capital Medical University, 56 South Lishi Road, Beijing 100045, China. shenqlyishi@163.com
Key Words	Biliary atresia; Transient elastography; Fibroscan; Liver fibrosis; Liver biopsy
Core Tip	This study was designed to evaluate liver fibrosis using non-invasive transient elastography (Fibroscan) in comparison with liver biopsy in children with biliary atresia (BA). According to the METAVIR scoring system, in groups F2, F3 and F4, the mean liver stiffness measurement (LSM) was 9.10 ± 3.30 kPa, 11.02 ± 3.31 kPa and 22.86 ± 12.43 kPa, respectively. The AUC of LSM for ≥ F4 was 0.886. The cut-off value of LSM was 15.15 kPa for ≥ F4, with high sensitivity, specificity, positive predictive value and negative predictive value. In conclusion, Fibroscan can be effectively used as a non-invasive technique to assess liver fibrosis in children with BA.
Publish Date	2015-06-18 17:32
Citation	Shen QL, Chen YJ, Wang ZM, Zhang TC, Pang WB, Shu J, Peng CH. Assessment of liver fibrosis by Fibroscan as compared to liver biopsy in biliary atresia. World J Gastroenterol 2015; 21(22): 6931-6936
URL	http://www.wjgnet.com/1007-9327/full/v21/i22/6931.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i22.6931

Full Article (PDF)	WJG-21-6931.pdf
Full Article (Word)	WJG-21-6931.doc
Manuscript File	15513-Review.doc
Answering Reviewers	15513-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	15513-Conflict-of-intetest statement.pdf
Copyright License Agreement	15513-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	15513-Institutional review board statement.pdf
Peer-review Report	15513-Peer-review(s).pdf
Scientific Misconduct Check	15513-Scientific misconduct check.pdf
Scientific Editor Work List	15513-Scientific editor work list.pdf