Publication Name	World Journal of Respirology
Manuscript ID	15521
Country	Belgium

Received	2014-11-28 08:37
Peer-Review Started	2014-11-29 13:24
To Make the First Decision	2014-12-12 17:32
Return for Revision	2014-12-18 12:20
Revised	2015-03-27 05:58
Second Decision	2015-05-29 15:20
Accepted by Journal Editor-in-Chief	2015-05-31 03:04
Accepted by Executive Editor-in-Chief	2015-06-08 15:55
Articles in Press	2015-06-08 16:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-13 09:41
Publish the Manuscript Online	2015-08-04 12:43

ISSN	2218-6255 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Respiratory System
Manuscript Type	Minireviews
Article Title	Unresectable stage Ⅲ non-small-cell lung cancer: Have we made any progress?
Manuscript Source	Invited Manuscript
All Author List	Carolien De Tollenaere, Yolande Lievens, Katrien Vandecasteele, Karim Vermaelen and Veerle Surmont
Funding Agency and Grant Number
Corresponding Author	Carolien De Tollenaere, MD, Department of Respiratory Medicine, University Hospital of Ghent, De Pintelaan 185, 9000 Ghent, Belgium. carolien.detollenaere@telenet.be
Key Words	Stage Ⅲ non-small-cell lung carcinoma; Chemoradiotherapy; Induction chemotherapy; Molecular targeted therapy; Consolidation chemotherapy; Dose-escalation; Altered fractionation; Advanced radiotherapy techniques; Prophylactic cranial irradiation
Core Tip	Lung cancer is responsible for the most cancer deaths. One third of patients have unresectable stage ⅢA/ⅢB disease. Despite a lot of efforts, local control and survival of these patients remains poor. Improving the treatment is therefore one of the biggest challenges in respiratory oncology. This review gives an overview of the important clinical studies that were performed the last decade in the treatment of unresectable stage Ⅲ non-small-cell lung carcinoma and focuses on im?provement of systemic therapy, with the exciting area of implementation of newer agents (targeted therapy and immunotherapy) and improvement of radiotherapy, including the potential of prophylactic cranial irradiation.
Publish Date	2015-08-04 12:43
Citation	De Tollenaere C, Lievens Y, Vandecasteele K, Vermaelen K, Surmont V. Unresectable stage Ⅲ non-small-cell lung cancer: Have we made any progress? World J Respirol 2015; 5(2): 140-151
URL	http://www.wjgnet.com/2218-6255/full/v5/i2/140.htm
DOI	http://dx.doi.org/10.5320/wjr.v5.i2.140

Full Article (PDF)	WJR-5-140.pdf
Full Article (Word)	WJR-5-140.doc
Manuscript File	15521-Review.docx
Answering Reviewers	15521-Answering reviewers.pdf
Audio Core Tip	15521-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15521-Conflict-of-interest statement.pdf
Copyright License Agreement	15521-Copyright assignment.pdf
Peer-review Report	15521-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15521-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15521-Scientific misconduct check.pdf
Scientific Editor Work List	15521-Scientific editor work list.pdf