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Articles Published Processes
5/20/2015 4:43:00 PM | Browse: 1336 | Download: 1716
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Received |
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2014-11-29 14:53 |
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Peer-Review Started |
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2014-11-29 17:28 |
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To Make the First Decision |
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2015-01-08 14:00 |
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Return for Revision |
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2015-01-14 14:07 |
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Revised |
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2015-01-19 23:41 |
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Second Decision |
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2015-03-09 09:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-03-18 16:45 |
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Articles in Press |
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2015-03-18 16:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-03-23 14:11 |
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Typeset the Manuscript |
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2015-05-11 19:04 |
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Publish the Manuscript Online |
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2015-05-20 16:43 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xin Zhang and Hui-Guo Ding |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Capital Science and Technology Development Foundation, Major Projects on Infectious Disease |
2012ZX1002-008-05 |
| High-Level Talent Academic Leader Training Program |
2011-2-19 |
| Capital Science and Tchnology Development Fund |
2014-1-2181 |
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| Corresponding Author |
Hui-Guo Ding, MD, PhD, Director of Gastroenterology and Hepatology, Department of Gastroenterology and Hepatology, Beijing You’an Hospital affiliated with Capital Medical University, Fengtai District, Beijing 100069,
China. dinghuiguo@medmail.com.cn
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| Key Words |
Hepatitis B virus; Mutations; Hepatocellular carcinoma; Carcinogenesis; Chronic hepatitis B |
| Core Tip |
This mini review fully describes the relationship between hepatitis B virus (HBV) genome mutations in different regions with liver disease progression and development to hepatocellular carcinoma (HCC) according to the recent data of mutations in chronic hepatitis B patients. Accordingly, the HBV mutations, either in the preS or PreC or/and core promoter region, are significantly associated with HCC and could be regarded as a biomarker to predict the occurrence of HCC.
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| Publish Date |
2015-05-20 16:43 |
| Citation |
Zhang X, Ding HG. Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinoma. World J Hepatol 2015; 7(9): 1282-1286 |
| URL |
http://www.wjgnet.com/1948-5182/full/v7/i9/1282.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v7.i9.1282 |
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