Publication Name	World Journal of Gastroenterology
Manuscript ID	15620
Country	China

Received	2014-11-30 19:40
Peer-Review Started	2014-11-30 19:52
To Make the First Decision	2015-01-08 16:58
Return for Revision	2015-01-13 12:03
Revised	2015-02-04 20:46
Second Decision	2015-03-25 16:28
Accepted by Journal Editor-in-Chief	2015-03-27 10:30
Accepted by Executive Editor-in-Chief	2015-03-31 10:45
Articles in Press	2015-03-31 11:08
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-05-19 07:03
Typeset the Manuscript	2015-06-29 17:14
Publish the Manuscript Online	2015-07-14 12:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Liuweiwuling tablets attenuate acetaminophen-induced acute liver injury and promote liver regeneration in mice
Manuscript Source	Unsolicited Manuscript
All Author List	Yan-Chang Lei, Wen Li and Pan Luo
Funding Agency and Grant Number
Corresponding Author	Yan-Chang Lei, Chief Physician, Department of Infectious Diseases, Zhejiang Hospital, No. 12 Lingyin Road, Hangzhou 310013, Zhejiang Province, China. ycleihust@sina.com
Key Words	Acute liver injury; Acetaminophen; Liuweiwuling tablets; Inflammatory cytokine; Liver regeneration
Core Tip	Clinical studies have shown that Liuweiwuling tablets are effective against a variety of liver injuries; however, its mechanism has not been established, especially for drug-induced liver injury. In this study, we found that Liuweiwuling tablets can attenuate acetaminophen-induced acute liver injury by decreasing inflammatory cytokine levels and promoting liver regeneration. Our results provide direct evidence for the effective therapy of liver damage with Liuweiwuling tablets and their value in clinical applications. Moreover, this is the first report showing that Liuweiwuling tablets can promote liver regeneration.
Publish Date	2015-07-14 12:17
Citation	Lei YC, Li W, Luo P. Liuweiwuling tablets attenuate acetaminophen-induced acute liver injury and promote liver regeneration in mice. World J Gastroenterol 2015; 21(26): 8089-8095
URL	http://www.wjgnet.com/1007-9327/full/v21/i26/8089.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i26.8089

Full Article (PDF)	WJG-21-8089.pdf
Full Article (Word)	WJG-21-8089.doc
Manuscript File	15620-Review.doc
Answering Reviewers	15620-Answering reviewers.pdf
Biostatistics Review Certificate	15620-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	15620-Conflict-of-interest statement.pdf
Copyright License Agreement	15620-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	15620-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	15620-Language certificate.pdf
Peer-review Report	15620-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15620-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15620-Scientific misconduct check.pdf
Scientific Editor Work List	15620-Scientific editor work list.pdf