Publication Name	World Journal of Gastroenterology
Manuscript ID	15698
Country	United States

Received	2014-12-04 08:14
Peer-Review Started	2014-12-04 12:23
To Make the First Decision	2015-03-10 20:10
Return for Revision	2015-03-12 09:19
Revised	2015-04-27 15:18
Second Decision	2015-06-08 08:06
Accepted by Journal Editor-in-Chief	2015-06-10 16:17
Accepted by Executive Editor-in-Chief	2015-06-26 14:58
Articles in Press	2015-06-26 14:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-10 17:36
Publish the Manuscript Online	2015-07-30 11:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Current and future treatments for hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Alexander Schlachterman, Willie W Craft Jr, Eric Hilgenfeldt, Avir Mitra and Roniel Cabrera
Funding Agency and Grant Number
Corresponding Author	Willie W Craft Jr, Assistant Director of Hospital Medicine, Upper Valley Medical Center, 3130 N County Rd 25A, Troy, OH 45373, United States. wcraf0@gmail.com
Key Words	Hepatocellular carcinoma; Hepatoma; Hepatocellular cancer; Liver cancer; Adult; Liver cell carcinoma; Liver cell carcinoma; Adult; Liver neoplasm; Hepatic neoplasm
Core Tip	Hepatocellular carcinoma (HCC), depending on the stage, has several treatment options including surgery, radiotherapy and biological agents such as Sorafenib. For both practitioners and patients these treatment modalities all offer advantages and disadvantages over one another. The question of when to use each modality remains an active field of debate. In order to provide clarity in this regard, we review currently used treatment methods along with the relevant data supporting or refuting them. Additionally, we then discuss molecular pathways involved in HCC that could be, and in some cases already are being, exploited for potential future drug therapy.
Publish Date	2015-07-30 11:17
Citation	Schlachterman A, Craft Jr WW, Hilgenfeldt E, Mitra A, Cabrera R. Current and future treatments for hepatocellular carcinoma. World J Gastroenterol 2015; 21(28): 8478-8491
URL	http://www.wjgnet.com/1007-9327/full/v21/i28/8478.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i28.8478

Full Article (PDF)	WJG-21-8478.pdf
Full Article (Word)	WJG-21-8478.doc
Manuscript File	15698-Review.docx
Answering Reviewers	15698-Answering reviewers.pdf
Audio Core Tip	15698-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15698-Conflict-of-interest statement.pdf
Copyright License Agreement	15698-Copyright assignment.pdf
Peer-review Report	15698-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15698-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15698-Scientific misconduct check.pdf
Scientific Editor Work List	15698-Scientific editor work list.pdf