Publication Name	World Journal of Gastroenterology
Manuscript ID	15847
Country	Romania

Received	2014-12-12 08:26
Peer-Review Started	2014-12-12 09:58
To Make the First Decision	2015-01-22 16:37
Return for Revision	2015-02-02 10:21
Revised	2015-02-26 00:00
Second Decision	2015-04-07 17:12
Accepted by Journal Editor-in-Chief	2015-04-10 21:46
Accepted by Company Editor-in-Chief	2015-04-17 15:05
Articles in Press	2015-04-17 16:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-14 15:54
Publish the Manuscript Online	2015-05-30 13:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	New targeted therapies in pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Andrada Seicean, Livia Petrusel and Radu Seicean
Funding Agency and Grant Number
Corresponding Author	Andrada Seicean, MD, PhD, Regional Institute of Gastroenterology and Hepatology, Iuliu Hatieganu University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca 400162, Romania. andradaseicean@gmail.com
Key Words	Immunotherapy; Pancreas neoplasm; Vaccines
Core Tip	Adjuvant therapy in pancreatic cancer has limited efficiency, and low survival rates are related to resistance to gemcitabine. New targeted therapies, such as passive immunotherapy, may have a role in combination with radiochemotherapy by targeting various protein kinases, as well as specific immunotherapies, such as vaccines, adoptive cell therapy and immunotherapy targeting tumor stem cells. In the future, treatments will likely include personalized medicine, tailored for numerous molecular therapeutic targets of multiple pathogenetic pathways.
Publish Date	2015-05-30 13:32
Citation	Seicean A, Petrusel L, Seicean R. New targeted therapies in pancreatic cancer. World J Gastroenterol 2015; 21(20): 6127-6145
URL	http://www.wjgnet.com/1007-9327/full/v21/i20/6127.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i20.6127

Full Article (PDF)	WJG-21-6127.pdf
Full Article (Word)	WJG-21-6127.doc
Manuscript File	15847-Review.docx
Answering Reviewers	15847-Answering reviewers.pdf
Audio Core Tip	15847-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15847-Conflict-of-interest statement.pdf
Copyright License Agreement	15847-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	15847-Language certificate.pdf
Peer-review Report	15847-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15847-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15847-Scientific misconduct check.pdf
Scientific Editor Work List	15847-Scientific editor work list.pdf