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12/2/2015 11:49:00 AM | Browse: 707 | Download: 1215
Publication Name World Journal of Clinical Oncology
Manuscript ID 15984
Country Italy
Received
2014-12-21 12:03
Peer-Review Started
2014-12-22 08:17
To Make the First Decision
2015-03-06 10:33
Return for Revision
2015-03-11 10:54
Revised
2015-03-19 00:30
Second Decision
2015-06-08 11:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-06-16 16:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-07-31 17:47
Publish the Manuscript Online
2015-08-17 16:41
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Isolated limb infusion chemotherapy with or without hemofiltration for recurrent limb melanoma
Manuscript Source Unsolicited Manuscript
All Author List Sara Cecchini, Donatella Sarti, Stefano Ricci, Ludovico Delle Vergini, Manuela Sallei, Stefano Serresi, Giuseppe Ricotti, Luca Mulazzani, Fabrizia Lattanzio and Giammaria Fiorentini
Funding Agency and Grant Number
Corresponding Author Dr. Giammaria Fiorentini, Department of Oncology-Hematology, “Azienda Ospedaliera Ospedali Riuniti Marche Nord”, PO San Salvatore, via C. Lombroso 1, 61122 Pesaro, Italy. giammaria.fiorentini@ospedalimarchenord.it
Key Words Metastatic melanoma; Melphalan; Intra-arterial infusion; Hemofiltration
Core Tip Isolated limb infusion (ILI) is a regional treatment of limb melanoma, allowing selective delivery of toxic agents to the arm or leg with the tumor, with limited leakage. Hemofiltration can reduce the high toxic peaks of drug in the blood, hence, limiting post-procedural side effects. In this paper we report results of an Italian Registry applying the ILI technique with or without Hemofiltration to recurrent non-resectable limb melanoma. The overall response rate was 66%. Low grade toxicity was observed in 90% of patients. ILI with/without hemofiltration is an efficacious and safe treatment for recurrent non-resectable limb melanoma.
Publish Date 2015-08-17 16:41
Citation Cecchini S, Sarti D, Ricci S, Vergini LD, Sallei M, Serresi S, Ricotti G, Mulazzani L, Lattanzio F, Fiorentini G. Isolated limb infusion chemotherapy with or without hemofiltration for recurrent limb melanoma. World J Clin Oncol 2015; 6(4): 57-63
URL http://www.wjgnet.com/2218-4333/full/v6/i4/57.htm
DOI http://dx.doi.org/10.5306/wjco.v6.i4.57
Full Article (PDF) WJCO-6-57.pdf
Full Article (Word) WJCO-6-57.doc
Manuscript File 15984-Review.doc
Answering Reviewers 15984-Answering reviewers.pdf
Audio Core Tip 15984-Audio core tip.mp3
Biostatistics Review Certificate 15984-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 15984-Conflict-of-interest statement.pdf
Copyright License Agreement 15984-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20141219205906.doc
Institutional Review Board Approval Form or Document 15984-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 15984-Language certificate.pdf
Peer-review Report 15984-Peer-review(s).pdf
Scientific Misconduct Check 15984-Scientific misconduct check.pdf
Scientific Editor Work List 15984-Scientific editor work list.pdf