Publication Name	World Journal of Gastroenterology
Manuscript ID	15988
Country	Italy

Received	2014-12-21 11:43
Peer-Review Started	2014-12-21 16:09
To Make the First Decision	2015-01-22 16:43
Return for Revision	2015-01-30 16:58
Revised	2015-02-11 19:16
Second Decision	2015-03-04 18:42
Accepted by Journal Editor-in-Chief	2015-03-05 00:20
Accepted by Executive Editor-in-Chief	2015-03-12 16:32
Articles in Press	2015-03-12 16:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-03 15:53
Publish the Manuscript Online	2015-04-20 15:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Management of hepatitis C infection before and after liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Stefano Fagiuoli, Roberto Ravasio, Maria Grazia Lucà, Anna Baldan, Silvia Pecere, Alessandro Vitale and Luisa Pasulo
Funding Agency and Grant Number
Corresponding Author	Dr. Stefano Fagiuoli, USC, Gastroenterology and Transplant Hepatology, Papa Giovanni XXIII Hospital, Piazza OMS, 1, 24127 Bergamo, Italy. sfagiuoli@hpg23.it
Key Words	Hepatitis C virus; Orthotopic liver transplantation; Interferon-free treatment; Decompensated cirrhosis; Chronic hepatitis C
Core Tip	This paper discusses alternative treatment options for patients with hepatitis C virus (HCV) undergoing liver transplantation (LT), particularly those with decompensated cirrhosis in whom interferon (IFN)-based therapy is contraindicated. Virtually all patients undergoing LT experience HCV recurrence leading to accelerated liver disease and cirrhosis development with reduced graft and patient survival. Novel IFN-free antiviral therapies featuring better efficacy and tolerability in such patients shall increase sustained virologic response rates while decreasing side effects and drug interactions, thus preventing progression of HCV-related liver disease, decreasing the general costs associated with both HCV treatment and worsening of patient health.
Publish Date	2015-04-20 15:10
Citation	Fagiuoli S, Ravasio R, Lucà MG, Baldan A, Pecere S, Vitale A, Pasulo L. Management of hepatitis C infection before and after liver transplantation. World J Gastroenterol 2015; 21(15): 4447-4456
URL	http://www.wjgnet.com/1007-9327/full/v21/i15/4447.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i15.4447

Full Article (PDF)	WJG-21-4447.pdf
Full Article (Word)	WJG-21-4447.doc
Manuscript File	15988-Review.docx
Answering Reviewers	15988-Answering reviewers.pdf
Audio Core Tip	15988-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	15988-Conflict-of-interest statement.pdf
Copyright License Agreement	15988-Copyright assignment.PDF
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20141219225201.pdf
Peer-review Report	15988-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	15988-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	15988-Scientific misconduct check.pdf
Scientific Editor Work List	15988-Scientific editor work list.pdf