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Articles Published Processes
7/6/2015 6:45:00 PM | Browse: 1294 | Download: 2274
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Received |
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2014-12-22 08:34 |
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Peer-Review Started |
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2014-12-23 22:56 |
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To Make the First Decision |
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2015-01-08 14:04 |
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Return for Revision |
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2015-01-13 09:14 |
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Revised |
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2015-02-03 06:31 |
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Second Decision |
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2015-04-01 15:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-04-14 16:08 |
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Articles in Press |
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2015-04-14 16:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-07-03 13:50 |
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Publish the Manuscript Online |
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2015-07-06 18:45 |
ISSN |
2220-6124 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Urology & Nephrology |
Manuscript Type |
Prospective Study |
Article Title |
Low T3 syndrome and long-term mortality in chronic hemodialysis patients
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Manuscript Source |
Invited Manuscript |
All Author List |
Stylianos Fragidis, Konstantinos Sombolos, Elias Thodis, Stylianos Panagoutsos, Euthymia Mourvati, Maria Pikilidou, Aikaterini Papagianni, Ploumis Pasadakis and Vasilios Vargemezis |
Funding Agency and Grant Number |
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Corresponding Author |
Stylianos Fragidis, MD, Department of Nephrology, Medical School, Democritus University of Thrace, University Campus, 68100 Alexadroupolis, Greece. sfragidis@yahoo.com |
Key Words |
C-reactive protein; Hemodialysis; Inflammation; Interleukin-6; Low T3 syndrome; Mortality |
Core Tip |
Monthly blood samples were obtained from 114 patients for three consecutive months during the observation period for evaluation of thyroid function and measurement of inflammatory markers high sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6). Patients were then followed-up for 7-years. Low mean freeT3 (< 1.8 pg/mL) emerged as a significant predictor of all-cause mortality after adjustment for age, diabetes mellitus, hypertension, hsCRP, serum creatinine and albumin. However, freeT3 was correlated with hsCRP, but not IL-6, and only at the first month suggesting that further studies are required to identify the underlying pathogenetic mechanisms of the association between thyroid function and survival. |
Publish Date |
2015-07-06 18:45 |
Citation |
Fragidis S, Sombolos K, Thodis E, Panagoutsos S, Mourvati E, Pikilidou M, Papagianni A, Pasadakis P, Vargemezis V. Low T3 syndrome and long-term mortality in chronic hemodialysis patients. World J Nephrol 2015; 4(3): 415-422 |
URL |
http://www.wjgnet.com/2220-6124/full/v4/i3/415.htm |
DOI |
http://dx.doi.org/10.5527/wjn.v4.i3.415 |
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