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8/20/2015 1:37:00 PM | Browse: 442 | Download: 380
Publication Name World Journal of Gastroenterology
Manuscript ID 16076
Country/Territory Canada
Received
2014-12-24 10:00
Peer-Review Started
2014-12-25 14:13
To Make the First Decision
2015-03-10 20:21
Return for Revision
2015-03-20 16:00
Revised
Second Decision
2015-06-10 09:16
Accepted by Journal Editor-in-Chief
2015-06-10 12:06
Accepted by Company Editor-in-Chief
2015-06-16 11:17
Articles in Press
2015-06-16 11:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-07-27 11:09
Publish the Manuscript Online
2015-08-20 13:37
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Editorial
Article Title Iron deficiency anemia in celiac disease
Manuscript Source Invited Manuscript
All Author List Hugh James Freeman
Funding Agency and Grant Number
Corresponding author Hugh Freeman, MD, CM, FRCPC, FACP, Professor, Department of Medicine (Gastroenterology), University of British Columbia, UBC Hospital, 2211 Wesbrook Mall, Vancouver, BC V6T 1W5, Canada. hugfree@shaw.ca
Keywords Anemia; Iron deficiency; Autoimmune hemolysis; Celiac disease; Iron absorption; Ferroportin; Hepcidin; Divalent metal transporter; Enterocyte
Core Tip Iron is a critical micronutrient that may be deficient in well-established celiac disease or be the presenting clinical feature even in the absence of diarrhea or weight loss. Most often, impaired duodenal mucosal uptake of iron is evident since surface absorptive area in the duodenum in reduced, in large part, because celiac disease is an immune-mediated disorder largely focused in the proximal small intestine. Other superimposed small intestinal complications of celiac disease may be responsible causing blood loss, including ulceration or neoplasia. Finally, associated gastric or colonic causes of blood loss, immune-mediated hemolysis and reduced expression of different regulatory proteins critical in iron uptake may be present.
Publish Date 2015-08-20 13:37
Citation Freeman HJ. Iron deficiency anemia in celiac disease. World J Gastroenterol 2015; 21(31): 9233-9238
Url http://www.wjgnet.com/1007-9327/full/v21/i31/9233.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i31.9233
Full Article (PDF) WJG-21-9233.pdf
Full Article (Word) WJG-21-9233.doc
Manuscript File 16076-Review.doc
Answering Reviewers 16076-Answering reviewers.pdf
Audio Core Tip 16076-Audio core tip.wma
Conflict-of-Interest Disclosure Form 16076-Conflict-of-interest statement.pdf
Copyright License Agreement 16076-Copyright assignment.pdf
Peer-review Report 16076-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16076-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16076-Scientific misconduct check.pdf
Scientific Editor Work List 16076-Scientific editor work list.pdf