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6/11/2015 10:11:00 AM | Browse: 1145 | Download: 2015
Publication Name World Journal of Gastroenterology
Manuscript ID 16083
Country/Territory China
Received
2014-12-26 09:31
Peer-Review Started
2014-12-26 13:09
To Make the First Decision
2015-01-22 16:48
Return for Revision
2015-01-27 14:59
Revised
Second Decision
2015-03-25 16:39
Accepted by Journal Editor-in-Chief
2015-03-26 18:27
Accepted by Company Editor-in-Chief
2015-04-03 13:44
Articles in Press
2015-04-03 13:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-04-17 16:05
Typeset the Manuscript
2015-05-20 18:08
Publish the Manuscript Online
2015-06-11 10:11
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Retrospective Study
Article Title Hepatitis B virus genotypes and genome characteristics in China
Manuscript Source Unsolicited Manuscript
All Author List Hong-Mei Li, Jian-Qiong Wang, Rui Wang, Qian Zhao, Li Li, Jin-Ping Zhang and Tao Shen
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81160352
Education Department Foundation of Yunnan Province 2012J091
Health Bureau of Yunnan Province D-201203 (partly)
Science and Technology Department of Yunnan Province 2013HB084 (partly)
Corresponding Author Dr. Tao Shen, Basic and Clinical Medicine Institute of Yunnan Province, Provincial Key Laboratory for Birth Defects and Genetic Diseases, the First People’s Hospital of Yunnan Province, Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan Province, China. ts902@126.com
Key Words Hepatitis B virus; Genotype; Phylogenetic tree; Clinical symptoms; Mutation; Codon usage bias
Core Tip This study recapitulated the epidemiology of hepatitis B virus (HBV) in China. Genotype C was the predominant HBV genotype in Northeastern, genotype B was predominant in Central Southern areas, genotype B and C were both dominant in Southwestern areas, and the recombinant genotype C/D was predominant in Northwestern areas. C2 and B2 were identified as the two major subgenotypes, FJ386674 might be a putative sub-genotype as B10. Moreover, the termination codon usage bias of B2 (TAA) and C2 (TGA) subtype and the correlation between HBV sequence mutations and clinical symptoms were also determined.
Publish Date 2015-06-11 10:11
Citation Li HM, Wang JQ, Wang R, Zhao Q, Li L, Zhang JP, Shen T. Hepatitis B virus genotypes and genome characteristics in China. World J Gastroenterol 2015; 21(21): 6684-6697
URL http://www.wjgnet.com/1007-9327/full/v21/i21/6684.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i21.6684
Full Article (PDF) WJG-21-6684.pdf
Full Article (Word) WJG-21-6684.doc
Manuscript File 16083-Review.docx
Answering Reviewers 16083-Answering reviewers.pdf
Audio Core Tip 16083-Audio core tip.mp3
Biostatistics Review Certificate 16083-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 16083-Conflict-of-interest statement.pdf
Copyright License Agreement 16083-Copyright assignment.pdf
Peer-review Report 16083-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16083-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16083-Scientific misconduct check.pdf
Scientific Editor Work List 16083-Scientific editor work list.pdf