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Articles Published Processes
8/17/2015 11:14:00 AM | Browse: 1119 | Download: 2279
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Received |
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2014-12-26 08:57 |
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Peer-Review Started |
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2014-12-26 15:21 |
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To Make the First Decision |
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2015-04-23 13:13 |
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Return for Revision |
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2015-04-29 17:47 |
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Revised |
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2015-05-14 23:05 |
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Second Decision |
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2015-06-03 08:52 |
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Accepted by Journal Editor-in-Chief |
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2015-06-04 10:07 |
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Accepted by Executive Editor-in-Chief |
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2015-06-10 16:32 |
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Articles in Press |
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2015-06-10 16:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-07-08 18:55 |
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Typeset the Manuscript |
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2015-07-31 11:29 |
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Publish the Manuscript Online |
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2015-08-17 11:15 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Basic Study |
| Article Title |
Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yukihito Ishii, Yu Motohashi, Makoto Muramatsu, Yoshiaki Katsuda, Katsuhiro Miyajima, Tomohiko Sasase, Takahisa Yamada, Tohru Matsui, Shinichi Kume and Takeshi Ohta |
| Funding Agency and Grant Number |
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| Corresponding Author |
Yukihito Ishii, PhD, Japan Tobacco Inc., Central Pharmaceutical Research Institute, 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan. yukihito.ishii@jt.com |
| Key Words |
Nonalcoholic steatohepatitis; Spontaneously diabetic Torii fatty rat; Fibrosis; Fatty liver; Metabolic syndrome |
| Core Tip |
Nonalcoholic steatohepatitis (NASH) is recognized as a major risk for progression to cirrhosis and liver failure or to hepatocellular carcinoma. In this study, we investigated the histological features of the liver in female spontaneously diabetic Torii (SDT) fatty rats. The SDT fatty rats exhibited pathophysiological features of NASH, and fibrosis appeared in the liver without dietary manipulation. Female SDT fatty rats have the potential to become an important animal model of NASH with type 2 diabetes and obesity, a condition for which few models currently exist. |
| Publish Date |
2015-08-17 11:15 |
| Citation |
Ishii Y, Motohashi Y, Muramatsu M, Katsuda Y, Miyajima K, Sasase T, Yamada T, Matsui T, Kume S, Ohta T. Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions. World J Gastroenterol 2015; 21(30): 9067-9078 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i30/9067.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i30.9067 |
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