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8/17/2015 11:14:00 AM | Browse: 481 | Download: 680
Publication Name World Journal of Gastroenterology
Manuscript ID 16097
Country/Territory Japan
Received
2014-12-26 08:57
Peer-Review Started
2014-12-26 15:21
To Make the First Decision
2015-04-23 13:13
Return for Revision
2015-04-29 17:47
Revised
2015-05-14 23:05
Second Decision
2015-06-03 08:52
Accepted by Journal Editor-in-Chief
2015-06-04 10:07
Accepted by Company Editor-in-Chief
2015-06-10 16:32
Articles in Press
2015-06-10 16:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-07-08 18:55
Typeset the Manuscript
2015-07-31 11:29
Publish the Manuscript Online
2015-08-17 11:15
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Physiology
Manuscript Type Basic Study
Article Title Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions
Manuscript Source Unsolicited Manuscript
All Author List Yukihito Ishii, Yu Motohashi, Makoto Muramatsu, Yoshiaki Katsuda, Katsuhiro Miyajima, Tomohiko Sasase, Takahisa Yamada, Tohru Matsui, Shinichi Kume and Takeshi Ohta
Funding Agency and Grant Number
Corresponding author Yukihito Ishii, PhD, Japan Tobacco Inc., Central Pharmaceutical Research Institute, 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan. yukihito.ishii@jt.com
Keywords Nonalcoholic steatohepatitis; Spontaneously diabetic Torii fatty rat; Fibrosis; Fatty liver; Metabolic syndrome
Core Tip Nonalcoholic steatohepatitis (NASH) is recognized as a major risk for progression to cirrhosis and liver failure or to hepatocellular carcinoma. In this study, we investigated the histological features of the liver in female spontaneously diabetic Torii (SDT) fatty rats. The SDT fatty rats exhibited pathophysiological features of NASH, and fibrosis appeared in the liver without dietary manipulation. Female SDT fatty rats have the potential to become an important animal model of NASH with type 2 diabetes and obesity, a condition for which few models currently exist.
Publish Date 2015-08-17 11:15
Citation Ishii Y, Motohashi Y, Muramatsu M, Katsuda Y, Miyajima K, Sasase T, Yamada T, Matsui T, Kume S, Ohta T. Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions. World J Gastroenterol 2015; 21(30): 9067-9078
Url http://www.wjgnet.com/1007-9327/full/v21/i30/9067.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i30.9067
Full Article (PDF) WJG-21-9067.pdf
Full Article (Word) WJG-21-9067.doc
Manuscript File 16097-Review.doc
Answering Reviewers 16097-Answering reviewers.pdf
Audio Core Tip 16097-Audio core tip.MP3
Biostatistics Review Certificate 16097-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 16097-Conflict-of-interest statement.pdf
Copyright License Agreement 16097-Copyright assignment.pdf
Data Sharing Statement 16097-Data sharing statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 16097-Institutional animal care and use committee statement .pdf
Institutional Review Board Approval Form or Document 16097-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 16097-Language certificate.pdf
Peer-review Report 16097-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16097-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16097-Scientific misconduct check.pdf
Scientific Editor Work List 16097-Scientific editor work list.pdf