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Articles Published Processes
6/20/2015 5:38:00 PM | Browse: 1202 | Download: 2944
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Received |
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2014-12-28 17:14 |
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Peer-Review Started |
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2014-12-29 13:48 |
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To Make the First Decision |
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2015-01-22 16:47 |
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Return for Revision |
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2015-01-26 19:56 |
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Revised |
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2015-02-03 15:28 |
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Second Decision |
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2015-03-11 15:38 |
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Accepted by Journal Editor-in-Chief |
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2015-03-12 10:07 |
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Accepted by Executive Editor-in-Chief |
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2015-03-19 17:39 |
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Articles in Press |
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2015-03-19 17:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-04-06 15:07 |
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Typeset the Manuscript |
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2015-06-03 18:05 |
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Publish the Manuscript Online |
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2015-06-20 17:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Autologous mobilized peripheral blood CD34+ cell infusion in non-viral decompensated liver cirrhosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mithun Sharma, Padaki Nagaraja Rao, Mitnala Sasikala, Mamata Reddy Kuncharam, Chima Reddy, Vardaraj Gokak, BPSS Raju, Jagdeesh R Singh, Piyal Nag and D Nageshwar Reddy |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Asian Healthcare Foundation |
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| Corresponding Author |
Mithun Sharma, MD, Department of Gastroenterology and Hepatology, Asian Institute of Gastroenterology, 6-3-661 Red Rose Café lane, Somajigudda, Hyderabad 500082, India. drmithunsharma@gmail.com |
| Key Words |
CD34 cell infusion; Stem cell; Cirrhosis; Model for End-Stage Liver Disease; Liver transplantation |
| Core Tip |
Cirrhosis of liver is a chronic progressive disease with high morbidity and mortality without liver transplantation. Alternative stem cell based therapies have shown promising results. In our study, we used autologous CD34 positive (CD34+) cell infusion in decompensated cirrhotic patients of non-viral etiology and is the first study which has compared them with controls who were selected from waiting list of liver transplantation. The results shows improvement in albumin at 1 mo and Model for End-Stage Liver Disease score at 3 mo. Though many questions still remain unanswered, stem cell therapy is a promising treatment modality and serve currently as a bridge to liver transplantation.
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| Publish Date |
2015-06-20 17:38 |
| Citation |
Sharma M, Rao PN, Sasikala M, Kuncharam MR, Reddy C, Gokak V, Raju BPSS, Singh JR, Nag P, Reddy DN. Autologous mobilized peripheral blood CD34+ cell infusion in non-viral decompensated liver cirrhosis. World J Gastroenterol 2015; 21(23): 7264-7271 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i23/7264.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i23.7264 |
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