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8/8/2015 1:55:00 PM | Browse: 1117 | Download: 1514
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Received |
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2015-01-02 10:29 |
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Peer-Review Started |
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2015-01-02 19:39 |
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To Make the First Decision |
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2015-01-20 13:28 |
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Return for Revision |
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2015-02-03 20:37 |
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Revised |
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2015-02-05 06:16 |
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Second Decision |
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2015-04-30 16:01 |
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Accepted by Journal Editor-in-Chief |
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2015-04-30 16:43 |
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Accepted by Executive Editor-in-Chief |
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2015-06-16 16:33 |
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Articles in Press |
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2015-06-16 16:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-07-17 17:33 |
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Publish the Manuscript Online |
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2015-08-08 13:55 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Editorial |
Article Title |
Selection tool alpha-fetoprotein for patients waiting for liver transplantation: How to easily manage a fractal algorithm
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Manuscript Source |
Invited Manuscript |
All Author List |
Quirino Lai, Giovanni Battista Levi Sandri and Jan Lerut |
Funding Agency and Grant Number |
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Corresponding Author |
Dr. Quirino Lai, MD, Transplant Unit, Department of Surgery, University Aquila, San Salvatore Hospital, Via Vetoio 1, 67010 Aquila, Italy. lai.quirino@libero.it
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Key Words |
Alpha-fetoprotein; Hepatocellular cancer; Milan criteria; Recurrence; Drop-out |
Core Tip |
Alpha-fetoprotein (AFP) behavior in patients with hepatocellular carcinoma waiting for liver trans-plant (LT) represents a perfect example of a fractal model. Consequently, AFP represents a useful but poorly mana-geable selection tool for patients waiting for LT. Looking at the recent literature, we can assume that: (1) last AFP value seem to be the best values to adopt; (2) different cut-offs may be adopted in the two different scenarios of Milan Criteria (MC) IN and MC OUT status; (3) AFP cut-off of 1000 ng/mL represent a good compromise for MC-IN patients; and (4) no definitive conclusion has been reached in relation to MC-OUT patients.
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Publish Date |
2015-08-08 13:55 |
Citation |
Lai Q, Levi Sandri GB, Lerut J. Selection tool alpha-fetoprotein for patients waiting for liver transplantation: How to easily manage a fractal algorithm. World J Hepatol 2015; 7(15): 1899-1904 |
URL |
http://www.wjgnet.com/1948-5182/full/v7/i15/1899.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v7.i15.1899 |
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