Publication Name	World Journal of Gastroenterology
Manuscript ID	16237
Country	Hungary

Received	2015-01-06 09:26
Peer-Review Started	2015-01-06 15:54
First Decision by Editorial Office Director
Return for Revision	2015-03-12 10:33
Revised	2015-03-24 18:11
Publication Fee Transferred
Second Decision by Editor	2015-04-23 08:08
Second Decision by Editor-in-Chief	2015-04-23 12:03
Final Decision by Editorial Office Director	2015-05-04 17:21
Articles in Press	2015-05-04 17:22
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-05 09:18
Publish the Manuscript Online	2015-06-20 17:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Prevalence and predictors of hospitalization in Crohn’s disease in a prospective population-based inception cohort from 2000-2012
Manuscript Source	Invited Manuscript
All Author List	Petra A Golovics, Laszlo Lakatos, Michael D Mandel, Barbara D Lovasz, Zsuzsanna Vegh, Zsuzsanna Kurti, Istvan Szita, Lajos S Kiss, Tunde Pandur and Peter L Lakatos
Funding Agency and Grant Number
Corresponding Author	Peter Laszlo Lakatos, MD, PhD, First Department of Medicine, Semmelweis University, Koranyi S. 2/A, H-1083 Hungary. lakatos.peter_laszlo@med.semmelweis-univ.hu
Key Words	Crohn’s disease; Hospitalization; Recurrence; Predictor; Population-based; Biological therapy
Core Tip	Recent data on hospitalization rates in Crohn’s disease (CD) are lacking from population-based studies. In the present study our aim was to analyze the prevalence, cause and predictors of hospitalization and re-hospitalization in the population-based inception cohort from Veszprem province. Relatively high rates of CD-related hospitalizations and re-hospitalizations were found in our cohort, especially during the first year after the diagnosis. Non-inflammatory disease behavior at diagnosis, behavior change in patients with initial B1 behavior, perianal disease and total AZA and anti-TNF exposure was associated with the time to first CD-related hospitalization. Early CD-related hospitalization was associated with non-inflammatory disease behavior, perianal or internal fistulizing disease, need for immunosuppressives and need for surgeries during the disease course.
Publish Date	2015-06-20 17:38
Citation	Golovics PA, Lakatos L, Mandel MD, Lovasz BD, Vegh Z, Kurti Z, Szita I, Kiss LS, Pandur T, Lakatos PL. Prevalence and predictors of hospitalization in Crohn’s disease in a prospective population-based inception cohort from 2000-2012. World J Gastroenterol 2015; 21(23): 7272-7280
URL	http://www.wjgnet.com/1007-9327/full/v21/i23/7272.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i23.7272

Full Article (PDF)	WJG-21-7272.pdf
Full Article (Word)	WJG-21-7272.doc
Manuscript File	16237-Review.doc
Answering Reviewers	16237-Answering reviewers.pdf
Audio Core Tip	16237-Audio core tip.mp3
Biostatistics Review Certificate	16237-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	16237-Conflict-of-interest statement.pdf
Copyright License Agreement	16237-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	16237-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	16237-Language certificate.pdf
Peer-review Report	16237-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16237-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16237-Scientific misconduct check.pdf
Scientific Editor Work List	16237-Scientific editor work list.pdf