Publication Name	World Journal of Gastroenterology
Manuscript ID	1629
Country	China

Received	2012-12-24 17:58
Peer-Review Started	2012-12-24 21:32
To Make the First Decision	2012-12-27 12:12
Return for Revision	2012-12-28 09:09
Revised	2013-01-04 14:42
Second Decision	2013-02-08 09:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-02-08 11:26
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-03-06 21:21
Typeset the Manuscript	2013-04-08 16:45
Publish the Manuscript Online	2013-04-19 20:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Increased international normalized ratio level in hepatocellular carcinoma patients with diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Hui Zhang, Chun Gao, Long Fang and Shu-Kun Yao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81273975 Research Fund of the China-Japan Friendship Hospital, Ministry of Health 2010-QN-01
Corresponding Author	Long Fang, MD, Department of Gastroenterology, China-Japan Friendship Hospital, Ministry of Health, No. 2 Yinghua East Road, Beijing 100029, China. longfang76@sohu.com
Key Words	International normalized ratio; Coagulation function; Diabetes mellitus; Hepatocellular carcinoma; Chinese patients
Core Tip	This study showed that the international normalized ratio (INR) level was an independent variable associated with diabetes mellitus (DM) in hepatocellular carcinoma (HCC) patients compared with those HCC patients without DM, after controlling for the confounding effect of age, systolic blood pressure, hemoglobin, platelet and hepatitis B virus infection by logistic analyses. Considering the effect of liver cirrhosis on results, a sub-group analysis was performed and the study population was restricted to those HCC patients with cirrhosis. A similar result was obtained. These results indicated that INR level was increased in HCC patients with DM and this is independent of liver cirrhosis.
Publish Date	2013-04-19 20:40
Citation	Zhang H, Gao C, Fang L, Yao SK. Increased international normalized ratio level in hepatocellular carcinoma patients with diabetes mellitus. World J Gastroenterol 2013; 19(15): 2395-2403
URL	http://www.wjgnet.com/1007-9327/full/v19/i15/2395.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i15.2395

Full Article (PDF)	WJG-19-2395.pdf
Manuscript File	1629-Review.doc
Answering Reviewers	1629-Answering reviewers.doc
Copyright License Agreement	1629-Copyright assignment.doc
Peer-review Report	1629-Peer reviews.docx
Scientific Editor Work List	1629-Scientific editor work list.doc