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Articles Published Processes
9/16/2014 11:44:00 AM | Browse: 1121 | Download: 936
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Received |
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2012-12-24 19:47 |
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Peer-Review Started |
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2012-12-24 21:15 |
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To Make the First Decision |
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2013-01-24 18:46 |
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Return for Revision |
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2013-01-25 17:09 |
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Revised |
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2013-02-03 23:21 |
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Second Decision |
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2013-02-07 09:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-02-07 10:15 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-04-24 14:50 |
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Publish the Manuscript Online |
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2013-05-07 10:53 |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
CD133: A cancer stem cells marker, is used in colorectal cancers
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Manuscript Source |
Invited Manuscript |
All Author List |
Fei Ren, Wei-Qi Sheng and Xiang Du |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Clinical Key Discipline Fund by Ministry of Health |
2010-2012 |
Chinese National Clinical Key Discipline |
2011-2012 |
Shanghai Science and Technology Commission of Shanghai Municipality |
10DJ1400500 |
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Corresponding Author |
Xiang Du, MD, PhD, Department of Pathology, Shanghai Cancer Center, Fudan University, 270 Dong An Road, Shanghai 200032, China. dx2008cn@yahoo.com.cn
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Key Words |
CD133; Colorectal cancer; Cancer stem cells; Prognosis; Chemoradiotherapy resistance |
Core Tip |
CD133 is not a reliable marker to identify the entire population of cancer stem cells (CSCs). However, the abundance of CD133 may be a good indicator of CSC identity and consistent with the biological characteristics of CSCs; The expression of CD133 is correlated to the poor survival; CD133(+) cells exhibit more chemoresistant behavior than CD133(-) cells; Whether CD133-targeting therapies can be a specific or efficient treatment for colorectal cancer has not been confirmed.
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Publish Date |
2013-05-07 10:53 |
Citation |
Ren F, Sheng WQ, Du X. CD133: A cancer stem cells marker, is used in colorectal cancers. World J Gastroenterol 2013; 19(17): 2603-2611 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i17/2603.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i17.2603 |
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