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Articles Published Processes
9/14/2015 4:53:00 PM | Browse: 1068 | Download: 1783
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Received |
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2015-01-14 18:54 |
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Peer-Review Started |
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2015-01-15 08:45 |
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To Make the First Decision |
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2015-03-26 18:22 |
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Return for Revision |
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2015-03-27 11:51 |
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Revised |
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Second Decision |
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2015-06-03 07:50 |
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Accepted by Journal Editor-in-Chief |
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2015-06-03 15:07 |
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Accepted by Executive Editor-in-Chief |
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2015-06-10 16:13 |
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Articles in Press |
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2015-06-10 16:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-08-10 10:05 |
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Typeset the Manuscript |
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2015-08-28 09:17 |
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Publish the Manuscript Online |
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2015-09-14 16:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Basic Study |
| Article Title |
Neurochemical features of endomorphin-2-containing neurons in the submucosal plexus of the rat colon
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun-Ping Li, Ting Zhang, Chang-Jun Gao, Zhen-Zhen Kou, Xu-Wen Jiao, Lian-Xiang Zhang, Zhen-Yu Wu, Zhong-Yi He and Yun-Qing Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
30971123 |
| National Natural Science Foundation of China |
81371239 |
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| Corresponding Author |
Dr. Yun-Qing Li, Department of Anatomy, Histology and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, No. 169 Changle West Road, Xi’an 710032, Shaanxi Province, China. deptanat@fmmu.edu.cn |
| Key Words |
Endomorphin-2; Submucosal plexus; Enteric neuron; Colon; μ-opioid receptor |
| Core Tip |
Previous studies have showed that morphine can cause gastrointestinal disorders via ?-opioid receptor (MOR). However, the regulatory mechanisms of MOR relating to gastrointestinal activity remain unclear. Endomorphin-2 (EM-2) is the endogenous ligand for the MOR. The distribution of EM-immunoreactive (IR) structures is generally similar to that of the MOR in the nervous system, but not the submucosal plexus of the enteric nervous system. This study demonstrates for the first time that EM-2-IR neurons are present in the submucosal plexus of the rat colon, and EM-2 co-localized with several neurochemical makers in distinct populations of submucosal neurons. |
| Publish Date |
2015-09-14 16:54 |
| Citation |
Li JP, Zhang T, Gao CJ, Kou ZZ, Jiao XW, Zhang LX, Wu ZY, He ZY, Li YQ. Neurochemical features of endomorphin-2-containing neurons in the submucosal plexus of the rat colon. World J Gastroenterol 2015; 21(34): 9936-9944 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i34/9936.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i34.9936 |
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