Publication Name	World Journal of Gastroenterology
Manuscript ID	16388
Country	China

Received	2015-01-16 09:04
Peer-Review Started	2015-01-16 13:58
To Make the First Decision	2015-03-10 20:35
Return for Revision	2015-03-12 10:18
Revised	2015-03-26 23:34
Second Decision	2015-04-27 08:31
Accepted by Journal Editor-in-Chief	2015-04-27 16:47
Accepted by Executive Editor-in-Chief	2015-05-04 18:18
Articles in Press	2015-05-04 18:18
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-06-08 06:29
Typeset the Manuscript	2015-06-26 15:26
Publish the Manuscript Online	2015-07-22 13:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Acupuncture and regulation of gastrointestinal function
Manuscript Source	Unsolicited Manuscript
All Author List	Hui Li, Tian He, Qian Xu, Zhe Li, Yan Liu, Fang Li, Bo-Feng Yang and Cun-Zhi Liu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81222050 National Natural Science Foundation of China 81303122 Beijing Natural Science Foundation 7144215 Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support ZYLX201412 National Basic Research Program of China（973 Program） 2014CB543203
Corresponding Author	Dr. Cun-Zhi Liu, Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, No. 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China. lcz623780@126.com
Key Words	Acupuncture; Gastrointestinal motility; Gastrointestinal barrier; Visceral sensitivity; Brain-gut axis
Core Tip	Acupuncture has been used as an appropriate adjunctive treatment for gastrointestinal (GI) dysfunction diseases. However, the therapeutic effects and underlying mechanisms in treating GI dysfunction have not yet been established due to a lack of systematic and comprehensive review articles. This review clarifies the effects and underlying mechanisms of acupuncture on GI function from various perspectives including GI motility, visceral sensitivity, the GI barrier, and the brain–gut axis. In addition, the dual regulatory effects and the intensity-dependent nature of acupuncture on GI motility were discussed. Acupuncture has been used as an appropriate adjunctive treatment for gastrointestinal (GI) dysfunction diseases. However, the therapeutic effects and underlying mechanisms in treating GI dysfunction have not yet been established due to a lack of systematic and comprehensive review articles. This review clarifies the effects and underlying mechanisms of acupuncture on GI function from various perspectives including GI motility, visceral sensitivity, the GI barrier, and the brain–gut axis. In addition, the dual regulatory effects and the intensity-dependent nature of acupuncture on GI motility were discussed.
Publish Date	2015-07-22 13:58
Citation	Li H, He T, Xu Q, Li Z, Liu Y, Li F, Yang BF, Liu CZ. Acupuncture and regulation of gastrointestinal function. World J Gastroenterol 2015; 21(27): 8304-8313
URL	http://www.wjgnet.com/1007-9327/full/v21/i27/8304.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i27.8304

Full Article (PDF)	WJG-21-8304.pdf
Full Article (Word)	WJG-21-8304.doc
Manuscript File	16388-Review.doc
Answering Reviewers	16388-Answering reviewers.pdf
Audio Core Tip	16388-Audio core tip.wav
Conflict-of-Interest Disclosure Form	16388-Conflict-of-interest statement.pdf
Copyright License Agreement	16388-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	16388-Language certificate.pdf
Peer-review Report	16388-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16388-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16388-Scientific misconduct check.pdf
Scientific Editor Work List	16388-Scientific editor work list.pdf