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9/18/2015 10:11:00 AM | Browse: 805 | Download: 1725
Publication Name World Journal of Gastroenterology
Manuscript ID 16400
Country China
Received
2015-01-15 17:37
Peer-Review Started
2015-01-16 14:09
To Make the First Decision
2015-03-10 20:41
Return for Revision
2015-03-12 10:50
Revised
2015-03-25 21:46
Second Decision
2015-04-21 12:18
Accepted by Journal Editor-in-Chief
2015-04-21 14:29
Accepted by Company Editor-in-Chief
2015-04-28 17:59
Articles in Press
2015-04-28 17:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-08-25 16:23
Typeset the Manuscript
2015-08-31 16:48
Publish the Manuscript Online
2015-09-18 10:11
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Mechanism of QHF-cisplatin against hepatocellular carcinoma in a mouse model
Manuscript Source Unsolicited Manuscript
All Author List Tao Chen, Shen-Jun Yuan, Jing Wang and Wei Hu
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Hubei Province, China 2011CAD039
Corresponding Author Dr. Tao Chen, The third level of TCM Pharmacology Research Laboratory affiliated to China TCM Administration, Medical Science College of China Three Gorges University, No. 8 Daxue Road, Yichang 443002, HubeI Province, China. chentao@ctgu.edu.cn
Key Words QHF formula; Cisplatin; Hepatocellular carcinoma; H22 cells; Hepatocyte growth factor/c-mesenchymal-epithelial transition factor
Core Tip Both QHF and DDP have anti-angiogenic effects in H22 hepatocellular carcinoma in mice. QHF in combination with small-dose DDP has synergistic anti-angiogenic effects and can improve the quality of survival and reduce the incidence of toxic reactions in mice with H22 hepatocellular carcinoma. Besides, QHF can significantly decrease the expression of hepatocyte growth factor, phosphorylated-mesenchymal-epithelial transition factor in the liver tumor tissue.
Publish Date 2015-09-18 10:11
Citation Chen T, Yuan SJ, Wang J, Hu W. Mechanism of QHF-cisplatin against hepatocellular carcinoma in a mouse model. World J Gastroenterol 2015; 21(35): 10126-10136
URL http://www.wjgnet.com/1007-9327/full/v21/i35/10126.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i35.10126
Full Article (PDF) WJG-21-10126.pdf
Full Article (Word) WJG-21-10126.doc
Manuscript File 16400-Review.doc
Answering Reviewers 16400-Answering reviewers.pdf
Audio Core Tip 16400-Audio core tip.mp3
Biostatistics Review Certificate 16400-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 16400-Conflict-of-interest statement.pdf
Copyright License Agreement 16400-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 16400-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 16400-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 16400-Language certificate.pdf
Peer-review Report 16400-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16400-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16400-Scientific misconduct check.pdf
Scientific Editor Work List 16400-Scientific editor work list.pdf