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Articles Published Processes
7/14/2015 12:17:00 PM | Browse: 1203 | Download: 1728
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Received |
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2015-01-15 17:43 |
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Peer-Review Started |
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2015-01-16 15:40 |
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To Make the First Decision |
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2015-02-10 15:56 |
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Return for Revision |
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2015-02-13 12:23 |
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Revised |
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2015-03-04 11:43 |
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Second Decision |
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2015-04-16 11:53 |
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Accepted by Journal Editor-in-Chief |
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2015-04-16 13:27 |
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Accepted by Executive Editor-in-Chief |
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2015-04-28 18:00 |
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Articles in Press |
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2015-04-28 18:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-06-08 21:50 |
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Typeset the Manuscript |
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2015-07-02 09:51 |
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Publish the Manuscript Online |
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2015-07-14 12:17 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Ameliorative effects of lutein on non-alcoholic fatty liver disease in rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiang Qiu, Dan-Hong Gao, Xiao Xiang, Yu-Fang Xiong, Teng-Shi Zhu, Lie-Gang Liu, Xiu-Fa Sun and Li-Ping Hao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High-tech R&D Program of China (863 Program) |
2010AA023003 |
| National Natural Science Foundation of China |
NSFC-81172657 |
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| Corresponding Author |
Li-Ping Hao, MD, PhD, Associate Professor, Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030, China. haolp@mails.tjmu.edu.cn |
| Key Words |
Lutein; Non-alcoholic fatty liver disease; Insulin resistance; Sirtuin 1; Peroxisome proliferators activated receptor-α |
| Core Tip |
Lutein has potential positive effects on chronic diseases. To date, no previous studies have reported the regulatory effects of lutein on non-alcoholic fatty liver disease (NAFLD). We observed that lutein has positive effects on hepatic lipid accumulation, liver function, and insulin resistance induced by a high-fat diet, possibly via activation of the expression of sirtuin 1 and, subsequently, peroxisome proliferators activated receptor-α, and other key factors in insulin signaling. These findings provide a new prospect for preventing NAFLD. |
| Publish Date |
2015-07-14 12:17 |
| Citation |
Qiu X, Gao DH, Xiang X, Xiong YF, Zhu TS, Liu LG, Sun XF, Hao LP. Ameliorative effects of lutein on non-alcoholic fatty liver disease in rats. World J Gastroenterol 2015; 21(26): 8061-8072 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i26/8061.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i26.8061 |
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