| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Cardiac mucosa at the gastroesophageal junction: An Eastern perspective
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ahrong Kim, Won-Young Park, Nari Shin, Hyun Jung Lee, Young Keum Kim, So Jeong Lee, Cheong-Soo Hwang, Do Youn Park, Gwang Ha Kim, Bong Eun Lee and Hong-Jae Jo |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National R and D Program for Cancer Control, Ministry for Health, Welfare, and Family affairs, South Korea |
0920050 |
|
| Corresponding Author |
Do Youn Park, MD, PhD, Department of Pathology, BioMedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan 602-739, South Korea. pdy220@pusan.ac.kr |
| Key Words |
Cardiac mucosa; Carditis; Gastroesophageal junction; Gastroesophageal reflux disease; Histopathology |
| Core Tip |
Incidence of gastroesophageal reflux disease and gastroesophageal junction (GEJ) adenocarcinomas is increasing in Asia, though with a lower prevalence than Western countries. The existence and origin of cardiac mucosa (CM) at the GEJ is debated, but most data were from a Western population. This study shows that CM at the GEJ is a common histologic finding in a chiefly Korean population, and 4.4% showed direct continuity of oxyntic mucosa and squamous epithelium even in single biopsy specimens. CM was associated with gastroesophageal reflux disease and carditis severity, suggesting CM may be an acquired structure and is associated with reflux stimuli, similar to results from Western populations. |
| Publish Date |
2015-08-17 11:15 |
| Citation |
Kim A, Park WY, Shin N, Lee HJ, Kim YK, Lee SJ, Hwang CS, Park DY, Kim GH, Lee BE, Jo HJ. Cardiac mucosa at the gastroesophageal junction: An Eastern perspective. World J Gastroenterol 2015; 21(30): 9126-9133 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i30/9126.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i30.9126 |
