Publication Name	World Journal of Psychiatry
Manuscript ID	16432
Country	Germany

Received	2015-01-20 10:34
Peer-Review Started	2015-01-22 14:52
To Make the First Decision	2015-02-07 14:54
Return for Revision	2015-02-10 14:43
Revised	2015-02-23 16:53
Second Decision	2015-03-16 18:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-08 09:12
Articles in Press	2015-04-08 09:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-09 09:18
Publish the Manuscript Online	2015-06-19 13:50

ISSN	2220-3206 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Psychiatry
Manuscript Type	Editorial
Article Title	What is schizophrenia? 25 years of research into schizophrenia - the Age Beginning Course Study
Manuscript Source	Invited Manuscript
All Author List	Heinz Häfner
Funding Agency and Grant Number	Funding Agency Grant Number German Research Foundation
Corresponding Author	Heinz Häfner, MD, PhD, Dr. h.c. mult., Professor Emeritus of Psychiatry, Head, Schizophrenia Research Group, Central Institute of Mental Health, Mannheim Faculty of Medicine/University of Heidelberg, J5, D-68159 Mannheim, Germany. heinz.haefner@zi-mannheim.de
Key Words	Schizophrenia and depression; Symptom dimensions; Types of illness course; Sex; Age
Core Tip	We studied schizophrenia from onset to 134 mo following first admission: age at onset is higher for women because of oestrogen. Prodromal schizophrenia and depression split diagnostically only after the onset of positive symptoms. Illness course exhibits a plateau after three years, positive symptoms do so after two, depressive and negative symptoms after three to five years. Depressive mood is the most prevalent symptom. Male first episodes are more frequent and more severe in the first half of life, female ones in the second half. Late-onset schizophrenias feature paranoid delusions, early-onset illnesses various severe pathology. Aetiological conclusions will be drawn.
Publish Date	2015-06-19 13:50
Citation	Häfner H. What is schizophrenia? 25 years of research into schizophrenia - the Age Beginning Course Study. World J Psychiatr 2015; 5(2): 167-169
URL	http://www.wjgnet.com/2220-3206/full/v5/i2/167.htm
DOI	http://dx.doi.org/10.5498/wjp.v5.i2.167

Full Article (PDF)	WJP-5-167.pdf
Full Article (Word)	WJP-5-167.doc
Manuscript File	16432-Review.doc
Answering Reviewers	16432-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	16432-Conflict-of-interest statement.pdf
Copyright License Agreement	16432-Copyright assignment.pdf
Peer-review Report	16432-Peer-review(s).pdf
Scientific Misconduct Check	16432-Scientific misconduct check.pdf
Scientific Editor Work List	16432-Scientific editor work list.pdf