Publication Name	World Journal of Hepatology
Manuscript ID	16480
Country	Japan

Received	2015-01-20 09:58
Peer-Review Started	2015-01-20 14:11
To Make the First Decision	2015-02-07 15:00
Return for Revision	2015-02-12 13:46
Revised	2015-02-14 17:23
Second Decision	2015-03-13 09:16
Accepted by Journal Editor-in-Chief	2015-03-14 23:52
Accepted by Executive Editor-in-Chief	2015-04-02 15:49
Articles in Press	2015-04-02 15:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-02 15:44
Publish the Manuscript Online	2015-05-20 16:43

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Editorial
Article Title	Ethanol-induced hepatic autophagy: Friend or foe?
Manuscript Source	Invited Manuscript
All Author List	Nabil Eid, Yuko Ito and Yoshinori Otsuki
Funding Agency and Grant Number
Corresponding Author	Nabil Eid, MD, PhD, Assistant Professor, Department of Anatomy and Cell Biology, Division of Life Sciences, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan. nabil@art.osaka-med.ac.jp
Key Words	Macrophages; Autophagy; Hepatocytes; Lipophagy; Mitophagy; Stellate cells; Alcohol
Core Tip	This short editorial discusses the impact of ethanol-induced upregulation of cytoprotective bulk and selective autophagy as mitophagy or lipohagy on various types of liver cells. While ethanol-induced activation of autophagy in hepatocytes is generally prosurvival mechanism, upregulation of autophagy in non-hepatocytes as stellate cells may stimulate fibrogenesis and subsequently induce detrimental effects on the liver as a whole. The autophagic response of other non-hepatocytes as macrophages and endothelial cells is unknown yet and needs to be investigated as these cells play important roles in ethanol-induced hepatic steatosis and damage.
Publish Date	2015-05-20 16:43
Citation	Eid N, Ito Y, Otsuki Y. Ethanol-induced hepatic autophagy: Friend or foe? World J Hepatol 2015; 7(9): 1154-1156
URL	http://www.wjgnet.com/1948-5182/full/v7/i9/1154.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i9.1154

Full Article (PDF)	WJH-7-1154.pdf
Full Article (Word)	WJH-7-1154.doc
Manuscript File	16480-Review.docx
Answering Reviewers	16480-Answering reviewers.pdf
Audio Core Tip	16480-Audio core tip.wav
Conflict-of-Interest Disclosure Form	16480-Conflict-of-interest statement.pdf
Copyright License Agreement	16480-Copyright assignment.pdf
Peer-review Report	16480-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16480-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16480-Scientific misconduct check.pdf
Scientific Editor Work List	16480-Scientific editor work list.pdf